(Q21981587)

Frizzled-6

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Frizzled/Smoothened, transmembrane domain, protein family

1 reference

inferred from protein domain or family

GPCR, family 2-like

1 reference

inferred from protein domain or family

Frizzled domain, protein family

1 reference

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

signal transducer activity

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61089&geneProductId=UniProtKB:Q61089

2 references

27 March 2018

Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61089&geneProductId=UniProtKB:Q61089

27 March 2018

Wnt-4 activates the canonical beta-catenin-mediated Wnt pathway and binds Frizzled-6 CRD: functional implications of Wnt/beta-catenin activity in kidney epithelial cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61089&geneProductId=UniProtKB:Q61089

transmembrane signaling receptor activity

IPI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

1 reference

14 February 2019

Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

Wnt-activated receptor activity

IPI

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

G protein-coupled receptor activity

IBA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

3 references

14 February 2019

Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

14 February 2019

Wnt-4 activates the canonical beta-catenin-mediated Wnt pathway and binds Frizzled-6 CRD: functional implications of Wnt/beta-catenin activity in kidney epithelial cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

1 reference

14 February 2019

The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

apicolateral plasma membrane

IDA

1 reference

14 February 2019

Asymmetric distribution of prickle-like 2 reveals an early underlying polarization of vestibular sensory epithelia in the inner ear

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

IDA

apical plasma membrane

1 reference

14 February 2019

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

cytoplasmic vesicle membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61089&geneProductId=UniProtKB:Q61089

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61089&geneProductId=UniProtKB:Q61089

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61089&geneProductId=UniProtKB:Q61089

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61089&geneProductId=UniProtKB:Q61089

integral component of membrane

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

integral component of membrane

IBA

The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells

2 references

biological process

Wnt signaling pathway

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

establishment of planar polarity

1 reference

14 February 2019

The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

multicellular organism development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells

inner ear morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

G protein-coupled receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

cell surface receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

nervous system development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

Wnt signaling pathway, planar cell polarity pathway

1 reference

14 February 2019

Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

embryonic nail plate morphogenesis

IDA

1 reference

14 February 2019

Frizzled6 deficiency disrupts the differentiation process of nail development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

1 reference

14 February 2019

Canonical Wnt signaling negatively regulates platelet function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

cell proliferation in midbrain

IMP

1 reference

14 February 2019

Fzd3 and Fzd6 deficiency results in a severe midbrain morphogenesis defect

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

1 reference

14 February 2019

Fzd3 and Fzd6 deficiency results in a severe midbrain morphogenesis defect

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

establishment of body hair planar orientation

1 reference

14 February 2019

Identification of Astrotactin2 as a Genetic Modifier That Regulates the Global Orientation of Mammalian Hair Follicles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

canonical Wnt signaling pathway

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61089

non-canonical Wnt signaling pathway

IBA

3 references

1 reference

GPCR, family 2-like

1 reference

Frizzled/Smoothened, transmembrane domain

1 reference