(Q21983287)

Immunoglobulin-like domain superfamily

1 reference

inferred from GOA cell component → membrane

membrane proteins

1 reference

based on heuristic

Signaling lymphocytic activation molecule, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

immunoglobulin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

5 references

14 February 2019

Identification and characterization of two related murine genes, Eat2a and Eat2b, encoding single SH2-domain adapters

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

14 February 2019

Genomic organization and characterization of mouse SAP, the gene that is altered in X-linked lymphoproliferative disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

14 February 2019

Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

14 February 2019

Association between SAP and FynT: Inducible SH3 domain-mediated interaction controlled by engagement of the SLAM receptor

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

14 February 2019

Influence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell function

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

integral component of membrane

IPI

cell component

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

1 reference

14 February 2019

Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

external side of plasma membrane

4 references

14 February 2019

Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

14 February 2019

MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

14 February 2019

Single-Stranded DNA-Binding Transcriptional Regulator FUBP1 Is Essential for Fetal and Adult Hematopoietic Stem Cell Self-Renewal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

14 February 2019

The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

natural killer cell differentiation

biological process

1 reference

14 February 2019

Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

adaptive immune response

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

immune system process

1 reference

14 February 2019

natural killer cell proliferation

1 reference

14 February 2019

Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

T-helper 1 cell cytokine production

1 reference

14 February 2019

Engagement of the signaling lymphocytic activation molecule (SLAM) on activated T cells results in IL-2-independent, cyclosporin A-sensitive T cell proliferation and IFN-gamma production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

negative regulation of T cell cytokine production

1 reference

14 February 2019

Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

regulation of vesicle fusion

1 reference

14 February 2019

Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

lymphocyte activation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

innate immune response

1 reference

14 February 2019

regulation of catalytic activity

1 reference

14 February 2019

Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

positive regulation of activated T cell proliferation

1 reference

14 February 2019

Engagement of the signaling lymphocytic activation molecule (SLAM) on activated T cells results in IL-2-independent, cyclosporin A-sensitive T cell proliferation and IFN-gamma production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

leukocyte chemotaxis involved in inflammatory response

1 reference

14 February 2019

Migration of myeloid cells during inflammation is differentially regulated by the cell surface receptors Slamf1 and Slamf8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

positive regulation of dendritic cell chemotaxis

1 reference

14 February 2019

Migration of myeloid cells during inflammation is differentially regulated by the cell surface receptors Slamf1 and Slamf8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

myeloid dendritic cell activation involved in immune response

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

negative regulation of interleukin-12 production

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

negative regulation of interleukin-6 production

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

negative regulation of tumor necrosis factor production

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

positive regulation of JNK cascade

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

positive regulation of ERK1 and ERK2 cascade

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

negative regulation of CD40 signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUM4

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QUM4&geneProductId=UniProtKB:Q9QUM4

Signaling lymphocytic activation molecule, N-terminal

has part(s)

1 reference

immunoglobulin-like domain

1 reference