(Q21984178)

http://www.ebi.ac.uk/interpro/protein/Q61616

membrane proteins

1 reference

based on heuristic

inferred from GOA cell component → membrane

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

dopamine neurotransmitter receptor activity

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Decrease of D2 receptor binding but increase in D2-stimulated G-protein activation, dopamine transporter binding and behavioural sensitization in brains of mice treated with a chronic escalating dose 'binge' cocaine administration paradigm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

5 references

8 April 2019

Drebrin depletion alters neurotransmitter receptor levels in protein complexes, dendritic spine morphogenesis and memory-related synaptic plasticity in the mouse hippocampus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Prostaglandin E receptor EP1 forms a complex with dopamine D1 receptor and directs D1-induced cAMP production to adenylyl cyclase 7 through mobilizing G(βγ) subunits in human embryonic kidney 293T cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

VPS35 regulates cell surface recycling and signaling of dopamine receptor D1

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

D1-like dopaminergic activation of phosphoinositide hydrolysis is independent of D1A dopamine receptors: evidence from D1A knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Mutation of SLC35D3 causes metabolic syndrome by impairing dopamine signaling in striatal D1 neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

dopamine neurotransmitter receptor activity, coupled via Gs

IPI

13 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

Altered striatal function in a mutant mouse lacking D1A dopamine receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

Distinct roles of D1 and D5 dopamine receptors in motor activity and striatal synaptic plasticity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

D1 receptors mediate dopamine action in the fetal suprachiasmatic nuclei: studies of mice with targeted deletion of the D1 dopamine receptor gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

Low affinity binding of the classical D1 antagonist SCH23390 in rodent brain: potential interaction with A2A and D2-like receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

Lesions of mouse striatum induced by 6-hydroxydopamine differentially alter the density, rate of synthesis, and level of gene expression of D1 and D2 dopamine receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

Dopamine D2 long receptor-deficient mice display alterations in striatum-dependent functions

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

Differences among mouse strains in the regulation by mu, delta 1 and delta 2 opioid receptors of striatal adenylyl cyclases activated by dopamine D1 or adenosine A2a receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

Mice lacking dopamine D2 and D3 receptors have spatial working memory deficits

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

signal transducer activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

G-protein alpha-subunit binding

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

G protein-coupled receptor activity

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

G-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

signaling receptor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

protein phosphatase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

angiotensin receptor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

D3 dopamine receptor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

protein-containing complex binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

protein heterodimerization activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

dopamine neurotransmitter receptor activity, coupled via Gs

14 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Distinct roles of D1 and D5 dopamine receptors in motor activity and striatal synaptic plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

D1 receptors mediate dopamine action in the fetal suprachiasmatic nuclei: studies of mice with targeted deletion of the D1 dopamine receptor gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Altered striatal function in a mutant mouse lacking D1A dopamine receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Low affinity binding of the classical D1 antagonist SCH23390 in rodent brain: potential interaction with A2A and D2-like receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Differences among mouse strains in the regulation by mu, delta 1 and delta 2 opioid receptors of striatal adenylyl cyclases activated by dopamine D1 or adenosine A2a receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Lesions of mouse striatum induced by 6-hydroxydopamine differentially alter the density, rate of synthesis, and level of gene expression of D1 and D2 dopamine receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Mice lacking dopamine D2 and D3 receptors have spatial working memory deficits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Dopamine D2 long receptor-deficient mice display alterations in striatum-dependent functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Altered striatal function in a mutant mouse lacking D1A dopamine receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

D1-like dopaminergic activation of phosphoinositide hydrolysis is independent of D1A dopamine receptors: evidence from D1A knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Differences among mouse strains in the regulation by mu, delta 1 and delta 2 opioid receptors of striatal adenylyl cyclases activated by dopamine D1 or adenosine A2a receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

D1 receptors mediate dopamine action in the fetal suprachiasmatic nuclei: studies of mice with targeted deletion of the D1 dopamine receptor gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

4 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

Mutation of SLC35D3 causes metabolic syndrome by impairing dopamine signaling in striatal D1 neurons

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

endoplasmic reticulum membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

integral component of plasma membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

Mutation of SLC35D3 causes metabolic syndrome by impairing dopamine signaling in striatal D1 neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

endoplasmic reticulum

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Mutation of SLC35D3 causes metabolic syndrome by impairing dopamine signaling in striatal D1 neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Mutation of SLC35D3 causes metabolic syndrome by impairing dopamine signaling in striatal D1 neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

IBA

glutamatergic synapse

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Dopamine synapse is a neuroligin-2-mediated contact between dopaminergic presynaptic and GABAergic postsynaptic structures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

A critical time window for dopamine actions on the structural plasticity of dendritic spines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

Dopamine synapse is a neuroligin-2-mediated contact between dopaminergic presynaptic and GABAergic postsynaptic structures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Drebrin depletion alters neurotransmitter receptor levels in protein complexes, dendritic spine morphogenesis and memory-related synaptic plasticity in the mouse hippocampus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

Ablation of D1 dopamine receptor-expressing cells generates mice with seizures, dystonia, hyperactivity, and impaired oral behavior.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

adenylate cyclase-activating G protein-coupled receptor signaling pathway

protein import into nucleus

1 reference

21 June 2018

A phosphatase cascade by which rewarding stimuli control nucleosomal response

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

Dopamine D1 receptors involved in locomotor activity and accumbens neural responses to prediction of reward associated with place

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

Simultaneous absence of dopamine D1 and D2 receptor-mediated signaling is lethal in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

Genetic evidence for the bidirectional modulation of synaptic plasticity in the prefrontal cortex by D1 receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

Hyperthermic and lethal effects of methamphetamine: roles of dopamine D1 and D2 receptors

temperature homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

6 references

8 April 2019

D1 receptors mediate dopamine action in the fetal suprachiasmatic nuclei: studies of mice with targeted deletion of the D1 dopamine receptor gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Behavioral responses to cocaine and amphetamine administration in mice lacking the dopamine D1 receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Binding of internalized receptors to the PDZ domain of GIPC/synectin recruits myosin VI to endocytic vesicles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

The dopamine D1 receptor is a critical mediator for cocaine-induced gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Lack of self-administration of cocaine in dopamine D1 receptor knock-out mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Paradoxical locomotor behavior of dopamine D1 receptor transgenic mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

3 references

8 April 2019

Differential effects of direct and indirect dopamine agonists on prepulse inhibition: a study in D1 and D2 receptor knock-out mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Role of dopamine D1 and D2 receptors in CRF-induced disruption of sensorimotor gating

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Accumbal dopamine D2 receptors are important for sensorimotor gating in C3H mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

dentate gyrus development

1 reference

8 April 2019

Ablation of D1 dopamine receptor-expressing cells generates mice with seizures, dystonia, hyperactivity, and impaired oral behavior.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

transmission of nerve impulse

1 reference

8 April 2019

Receptor subtypes involved in the presynaptic and postsynaptic actions of dopamine on striatal interneurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

Spatial learning deficit in dopamine D(1) receptor knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

positive regulation of synaptic transmission, glutamatergic

1 reference

8 April 2019

Modulatory actions of dopamine on NMDA receptor-mediated responses are reduced in D1A-deficient mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

Phenotypic resolution of spontaneous and D1-like agonist-induced orofacial movement topographies in congenic dopamine D1A receptor 'knockout' mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses

adult walking behavior

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Essential conservation of D1 mutant phenotype at the level of individual topographies of behaviour in mice lacking both D1 and D3 dopamine receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Dopamine D3 receptor mutant mice exhibit increased behavioral sensitivity to concurrent stimulation of D1 and D2 receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

Simultaneous absence of dopamine D1 and D2 receptor-mediated signaling is lethal in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

G protein-coupled receptor signaling pathway

IGI

4 references

8 April 2019

Galpha(olf) levels are regulated by receptor usage and control dopamine and adenosine action in the striatum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

G-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

adenylate cyclase-activating dopamine receptor signaling pathway

9 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

D1-like dopaminergic activation of phosphoinositide hydrolysis is independent of D1A dopamine receptors: evidence from D1A knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

Impaired D2 dopamine receptor function in mice lacking type 5 adenylyl cyclase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

Prostaglandin E receptor EP1 forms a complex with dopamine D1 receptor and directs D1-induced cAMP production to adenylyl cyclase 7 through mobilizing G(βγ) subunits in human embryonic kidney 293T cells.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

Differences among mouse strains in the regulation by mu, delta 1 and delta 2 opioid receptors of striatal adenylyl cyclases activated by dopamine D1 or adenosine A2a receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

21 June 2018

Motor dysfunction in type 5 adenylyl cyclase-null mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61616&geneProductId=UniProtKB:Q61616

Ablation of D1 dopamine receptor-expressing cells generates mice with seizures, dystonia, hyperactivity, and impaired oral behavior.

astrocyte development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

Dopamine-stimulated sexual behavior is testosterone dependent in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

Prolonged fear responses in mice lacking dopamine D1 receptor

behavioral fear response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

activation of adenylate cyclase activity

3 references

conditioned taste aversion

1 reference

8 April 2019

Mice lacking dopamine D1 receptors express normal lithium chloride-induced conditioned taste aversion for salt but not sucrose

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

cerebral cortex GABAergic interneuron migration

1 reference

8 April 2019

Dopamine receptor activation modulates GABA neuron migration from the basal forebrain to the cerebral cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

Blunted brain metabolic response to ketamine in mice lacking D(1A) dopamine receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

Role of D1-like receptors in amphetamine-induced behavioral sensitization: a study using D1A receptor knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

positive regulation of cell migration

IGI

1 reference

8 April 2019

Dopamine receptor activation modulates GABA neuron migration from the basal forebrain to the cerebral cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

regulation of dopamine metabolic process

1 reference

8 April 2019

The role of dopamine receptors in regulating the size of axonal arbors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

phospholipase C-activating dopamine receptor signaling pathway

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Enhancement of dopamine-induced signaling responses in the forebrain of mice lacking dopamine D3 receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

Galpha(olf) levels are regulated by receptor usage and control dopamine and adenosine action in the striatum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

Ablation of D1 dopamine receptor-expressing cells generates mice with seizures, dystonia, hyperactivity, and impaired oral behavior.

hippocampus development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

neuronal action potential

1 reference

8 April 2019

Binding of internalized receptors to the PDZ domain of GIPC/synectin recruits myosin VI to endocytic vesicles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

Distinct roles of D1 and D5 dopamine receptors in motor activity and striatal synaptic plasticity

long-term potentiation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Dopamine D1-deficient mutant mice do not express the late phase of hippocampal long-term potentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Genetic evidence for the bidirectional modulation of synaptic plasticity in the prefrontal cortex by D1 receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

Ablation of D1 dopamine receptor-expressing cells generates mice with seizures, dystonia, hyperactivity, and impaired oral behavior.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

Behavioral responses to cocaine and amphetamine administration in mice lacking the dopamine D1 receptor

response to amphetamine

8 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Effects of repeated amphetamine treatment on the locomotor activity of the dopamine D1A-deficient mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Expression of mutant NMDA receptors in dopamine D1 receptor-containing cells prevents cocaine sensitization and decreases cocaine preference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Paradoxical locomotor behavior of dopamine D1 receptor transgenic mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Hyperthermic and lethal effects of methamphetamine: roles of dopamine D1 and D2 receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Balanced NMDA receptor activity in dopamine D1 receptor (D1R)- and D2R-expressing medium spiny neurons is required for amphetamine sensitization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Mice lacking dopamine D2 and D3 receptors have spatial working memory deficits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Role of D1-like receptors in amphetamine-induced behavioral sensitization: a study using D1A receptor knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

regulation of protein phosphorylation

IGI

1 reference

8 April 2019

A phosphatase cascade by which rewarding stimuli control nucleosomal response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

positive regulation of protein phosphorylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

negative regulation of protein kinase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

intracellular protein transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

dopamine receptor signaling pathway

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Binding of internalized receptors to the PDZ domain of GIPC/synectin recruits myosin VI to endocytic vesicles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Mice lacking dopamine D2 and D3 receptors have spatial working memory deficits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Distinct functions of the two isoforms of dopamine D2 receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

13 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Behavioural assessment of mice lacking D1A dopamine receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Behavioral responses to cocaine and amphetamine administration in mice lacking the dopamine D1 receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Distinct roles of D1 and D5 dopamine receptors in motor activity and striatal synaptic plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Dopamine D1 receptors involved in locomotor activity and accumbens neural responses to prediction of reward associated with place

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Blunted brain metabolic response to ketamine in mice lacking D(1A) dopamine receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Effects of repeated amphetamine treatment on the locomotor activity of the dopamine D1A-deficient mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Paradoxical locomotor behavior of dopamine D1 receptor transgenic mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Ablation of D1 dopamine receptor-expressing cells generates mice with seizures, dystonia, hyperactivity, and impaired oral behavior.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Modification of dopamine D(1) receptor knockout phenotype in mice lacking both dopamine D(1) and D(3) receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of D1 and D2 receptor antagonists

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Simultaneous absence of dopamine D1 and D2 receptor-mediated signaling is lethal in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Modification of dopamine D(1) receptor knockout phenotype in mice lacking both dopamine D(1) and D(3) receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Behavioural assessment of mice lacking D1A dopamine receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Spatial learning deficit in dopamine D(1) receptor knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Dopamine D1 receptors involved in locomotor activity and accumbens neural responses to prediction of reward associated with place

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

regulation of vasoconstriction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

calcium-mediated signaling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

negative regulation of cell migration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

negative regulation of circadian sleep/wake cycle, sleep

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

regulation of ion transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

positive regulation of adenylate cyclase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

positive regulation of membrane potential

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

regulation of long-term neuronal synaptic plasticity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

negative regulation of cell death

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

positive regulation of long-term synaptic potentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

positive regulation of feeding behavior

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Action sequencing is impaired in D1A-deficient mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

The expression of neuropeptide-induced excessive grooming behavior in dopamine D1 and D2 receptor-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

adenylate cyclase-activating dopamine receptor signaling pathway

10 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

D1-like dopaminergic activation of phosphoinositide hydrolysis is independent of D1A dopamine receptors: evidence from D1A knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Impaired D2 dopamine receptor function in mice lacking type 5 adenylyl cyclase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Prostaglandin E receptor EP1 forms a complex with dopamine D1 receptor and directs D1-induced cAMP production to adenylyl cyclase 7 through mobilizing G(βγ) subunits in human embryonic kidney 293T cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Motor dysfunction in type 5 adenylyl cyclase-null mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Differences among mouse strains in the regulation by mu, delta 1 and delta 2 opioid receptors of striatal adenylyl cyclases activated by dopamine D1 or adenosine A2a receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

modification of postsynaptic structure

IBA

1 reference

8 April 2019

A critical time window for dopamine actions on the structural plasticity of dendritic spines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

postsynaptic modulation of chemical synaptic transmission

EXP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61616

GPCR, rhodopsin-like, 7TM

has part(s)

1 reference

stated in

InterPro Release 71.0