(Q21984184)

http://www.ebi.ac.uk/interpro/protein/Q8K4T5

Tyrosine specific protein phosphatases domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Dual specificity phosphatase

1 reference

based on heuristic

inferred from protein domain or family

Dual specificity protein phosphatase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

9 August 2016

language of work or name

1 reference

9 August 2016

language of work or name

English

molecular function

phosphoprotein phosphatase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

MAP-kinase scaffold activity

1 reference

14 February 2019

Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

mitogen-activated protein kinase kinase kinase binding

1 reference

14 February 2019

Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

protein kinase inhibitor activity

IPI

1 reference

14 February 2019

Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

protein kinase activator activity

1 reference

14 February 2019

Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

protein tyrosine/threonine phosphatase activity

1 reference

14 February 2019

A novel dual specificity phosphatase SKRP1 interacts with the MAPK kinase MKK7 and inactivates the JNK MAPK pathway. Implication for the precise regulation of the particular MAPK pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

1 reference

14 February 2019

Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

protein tyrosine phosphatase activity

IPI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

mitogen-activated protein kinase kinase binding

1 reference

14 February 2019

Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

JUN kinase phosphatase activity

1 reference

27 March 2018

A novel dual specificity phosphatase SKRP1 interacts with the MAPK kinase MKK7 and inactivates the JNK MAPK pathway. Implication for the precise regulation of the particular MAPK pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4T5&geneProductId=UniProtKB:Q8K4T5

JUN kinase phosphatase activity

1 reference

27 March 2018

A novel dual specificity phosphatase SKRP1 interacts with the MAPK kinase MKK7 and inactivates the JNK MAPK pathway. Implication for the precise regulation of the particular MAPK pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4T5&geneProductId=UniProtKB:Q8K4T5

negative regulation of protein kinase activity

1 reference

14 February 2019

Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

positive regulation of JUN kinase activity

1 reference

14 February 2019

Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

positive regulation of JNK cascade

1 reference

14 February 2019

Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

negative regulation of JNK cascade

1 reference

14 February 2019

Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

1 reference

14 February 2019

Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

peptidyl-tyrosine dephosphorylation

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

negative regulation of JUN kinase activity

1 reference

14 February 2019

Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

positive regulation of MAPK cascade

1 reference

14 February 2019

Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

positive regulation of protein kinase activity

1 reference

14 February 2019

Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

activation of protein kinase activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

regulation of MAP kinase activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4T5

Tyrosine specific protein phosphatases domain

IBA

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8K4T5

Dual specificity protein phosphatase domain

1 reference

stated in

InterPro Release 71.0