(Q21984344)

Protein kinase-like domain superfamily

1 reference

C2 domain superfamily

1 reference

membrane proteins

1 reference

inferred from GOA cell component → membrane

Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, protein family

1 reference

Protein kinase, C-terminal domain, protein family

1 reference

Diacylglycerol/phorbol-ester binding domain, protein family

1 reference

Novel protein kinase C theta, catalytic domain, protein family

1 reference

AGC-kinase, C-terminal domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Serine/threonine-protein kinase, active site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

protein kinase activity

1 reference

14 February 2019

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

protein kinase C activity

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

Functional association of cytokine-induced SH2 protein and protein kinase C in activated T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

3 references

14 February 2019

Nfix regulates fetal-specific transcription in developing skeletal muscle

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

2 references

protein serine/threonine kinase activity

protein serine/threonine kinase activity

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

Functional association of cytokine-induced SH2 protein and protein kinase C in activated T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

CD43 regulation of T cell activation is not through steric inhibition of T cell-APC interactions but through an intracellular mechanism

IDA

immunological synapse

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

CD4 raft association and signaling regulate molecular clustering at the immunological synapse site

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

Functional association of cytokine-induced SH2 protein and protein kinase C in activated T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

2 references

neuromuscular junction

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

regulation of transcription, DNA-templated

biological process

1 reference

14 February 2019

Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

immune system process

1 reference

14 February 2019

positive regulation of T-helper 2 cell activation

1 reference

14 February 2019

Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

positive regulation of interleukin-4 production

1 reference

14 February 2019

Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

negative regulation of T cell apoptotic process

3 references

negative regulation of insulin receptor signaling pathway

3 references

membrane protein ectodomain proteolysis

1 reference

14 February 2019

A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

peptidyl-serine phosphorylation

IDA

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

positive regulation of T-helper 17 type immune response

IBA

1 reference

14 February 2019

Resistance to experimental autoimmune encephalomyelitis and impaired IL-17 production in protein kinase C theta-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

positive regulation of T cell proliferation

1 reference

14 February 2019

Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

positive regulation of interleukin-17 production

1 reference

14 February 2019

Resistance to experimental autoimmune encephalomyelitis and impaired IL-17 production in protein kinase C theta-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

inflammatory response

1 reference

14 February 2019

regulation of platelet aggregation

1 reference

14 February 2019

PKCtheta is required for hemostasis and positive regulation of thrombin-induced platelet aggregation and alpha-granule secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

positive regulation of NF-kappaB transcription factor activity

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

regulation of G2/M transition of mitotic cell cycle

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

intracellular signal transduction

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02111&geneProductId=UniProtKB:Q02111

24 April 2018

Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02111&geneProductId=UniProtKB:Q02111

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02111&geneProductId=UniProtKB:Q02111

positive regulation of protein import into nucleus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

positive regulation of protein secretion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

positive regulation of filopodium assembly

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

positive regulation of stress fiber assembly

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

intracellular signal transduction

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02111

diacylglycerol/phorbol-ester binding

IBA

has part(s)

1 reference

AGC-kinase, C-terminal

1 reference

serine/threonine-protein kinase, active site

1 reference

protein kinase, C-terminal

1 reference

protein kinase, ATP binding site

1 reference

protein kinase C-like, phorbol ester/diacylglycerol-binding domain

1 reference

protein kinase domain

1 reference

Novel protein kinase C theta, catalytic domain

1 reference