(Q21984665)

Mitogen-activated protein kinase kinase kinase 12

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

inferred from protein domain or family

Protein kinase domain, protein family

1 reference

inferred from protein domain or family

Serine/threonine-protein kinase, active site, protein family

1 reference

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

protein kinase activity

1 reference

14 February 2019

protein homodimerization activity

1 reference

14 February 2019

Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

protein serine/threonine kinase activity

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60700&geneProductId=UniProtKB:Q60700

27 March 2018

Identification, molecular cloning, and characterization of dual leucine zipper bearing kinase. A novel serine/threonine protein kinase that defines a second subfamily of mixed lineage kinases

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60700&geneProductId=UniProtKB:Q60700

27 March 2018

Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60700&geneProductId=UniProtKB:Q60700

MAP kinase kinase kinase activity

2 references

2 references

signal transducer activity

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60700&geneProductId=UniProtKB:Q60700

protein serine/threonine kinase activity

IBA

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

14 February 2019

Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

14 February 2019

Identification, molecular cloning, and characterization of dual leucine zipper bearing kinase. A novel serine/threonine protein kinase that defines a second subfamily of mixed lineage kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

1 reference

14 February 2019

Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

1 reference

14 February 2019

The ubiquitin ligase Phr1 regulates axon outgrowth through modulation of microtubule dynamics

GOA

curator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

1 reference

27 March 2018

Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60700&geneProductId=UniProtKB:Q60700

1 reference

14 February 2019

The ubiquitin ligase Phr1 regulates axon outgrowth through modulation of microtubule dynamics

GOA

curator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

protein phosphorylation

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

14 February 2019

Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

peptidyl-serine phosphorylation

2 references

27 March 2018

Identification, molecular cloning, and characterization of dual leucine zipper bearing kinase. A novel serine/threonine protein kinase that defines a second subfamily of mixed lineage kinases

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60700&geneProductId=UniProtKB:Q60700

27 March 2018

Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60700&geneProductId=UniProtKB:Q60700

protein autophosphorylation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

14 February 2019

Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

14 February 2019

Identification, molecular cloning, and characterization of dual leucine zipper bearing kinase. A novel serine/threonine protein kinase that defines a second subfamily of mixed lineage kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

peptidyl-threonine phosphorylation

2 references

14 February 2019

Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

14 February 2019

Identification, molecular cloning, and characterization of dual leucine zipper bearing kinase. A novel serine/threonine protein kinase that defines a second subfamily of mixed lineage kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

negative regulation of motor neuron apoptotic process

1 reference

14 February 2019

ZPK/DLK and MKK4 form the critical gateway to axotomy-induced motoneuron death in neonates

GOA

curator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

peptidyl-serine phosphorylation

IBA

3 references

14 February 2019

Leucine Zipper-bearing Kinase promotes axon growth in mammalian central nervous system neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

14 February 2019

Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

14 February 2019

Identification, molecular cloning, and characterization of dual leucine zipper bearing kinase. A novel serine/threonine protein kinase that defines a second subfamily of mixed lineage kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60700

positive regulation of transcription, DNA-templated

3 references

positive regulation of ERK1 and ERK2 cascade

3 references

serine/threonine-protein kinase, active site

1 reference

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

protein kinase domain

1 reference