(Q21984733)

Protein kinase-like domain superfamily

1 reference

SH2 domain superfamily

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

SH2 domain, protein family

1 reference

SH3 domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Tyrosine-protein kinase, catalytic domain, protein family

1 reference

Tyrosine-protein kinase, active site, protein family

1 reference

protein domain specific binding

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

9 May 2019

Identification of a ten-amino acid proline-rich SH3 binding site

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

scaffold protein binding

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Caveolin-1 modulates cardiac gap junction homeostasis and arrhythmogenecity by regulating cSrc tyrosine kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Src-induced phosphorylation of caveolin-2 on tyrosine 19. Phospho-caveolin-2 (Tyr(P)19) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

27 references

9 May 2019

Src kinase activity is essential for osteoclast function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Delphilin: a novel PDZ and formin homology domain-containing protein that synaptically colocalizes and interacts with glutamate receptor delta 2 subunit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

The guanine nucleotide exchange factor Arhgef5 plays crucial roles in Src-induced podosome formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

A reactive oxygen species-mediated, self-perpetuating loop persistently activates platelet-derived growth factor receptor α

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Ccpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor Dbs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Dishevelled-2 docks and activates Src in a Wnt-dependent manner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

CXCR4-mediated bone marrow progenitor cell maintenance and mobilization are modulated by c-kit activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

A caveolin-3 mutant that causes limb girdle muscular dystrophy type 1C disrupts Src localization and activity and induces apoptosis in skeletal myotubes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Palmitoylation-dependent endosomal localization of AATYK1A and its interaction with Src

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Deficiency of a beta-arrestin-2 signal complex contributes to insulin resistance.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Nε-lysine acetylation determines dissociation from GAP junctions and lateralization of connexin 43 in normal and dystrophic heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Identification of profilin and src homology 3 domains as binding partners for Drosophila enabled

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Linker length dependent binding of a focal adhesion kinase derived peptide to the Src SH3-SH2 domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

A proteomics strategy for the enrichment of receptor-associated complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Roles of the SH2 and SH3 domains in the regulation of neuronal Src kinase functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Phosphorylation of receptor protein-tyrosine phosphatase alpha on Tyr789, a binding site for the SH3-SH2-SH3 adaptor protein GRB-2 in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

NKX2-1/TITF1/TTF-1-Induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

EphB receptors regulate dendritic spine morphogenesis through the recruitment/phosphorylation of focal adhesion kinase and RhoA activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Role of Src in C3 transient receptor potential channel function and evidence for a heterogeneous makeup of receptor- and store-operated Ca2+ entry channels

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Src kinase activation by direct interaction with the integrin β cytoplasmic domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

PSD-95 is a negative regulator of the tyrosine kinase Src in the NMDA receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Dramatic inhibition of osteoclast sealing ring formation and bone resorption in vitro by a WASP-peptide containing pTyr294 amino acid

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Mobility of TOAC spin-labelled peptides binding to the Src SH3 domain studied by paramagnetic NMR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

c-Src phosphorylation and activation of hexokinase promotes tumorigenesis and metastasis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Molecular mapping of tyrosine-phosphorylated proteins in focal adhesions using fluorescence resonance energy transfer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05480&geneProductId=UniProtKB:P05480

IPI

hormone receptor binding

1 reference

16 July 2018

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

growth factor receptor binding

protein kinase activity

8 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Abl family kinases regulate FcγR-mediated phagocytosis in murine macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Dishevelled-2 docks and activates Src in a Wnt-dependent manner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

A reactive oxygen species-mediated, self-perpetuating loop persistently activates platelet-derived growth factor receptor α

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

Regulation of connexin43 protein complexes by intracellular acidification

ephrin receptor binding

1 reference

9 May 2019

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

protein tyrosine kinase activity

IPI

8 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Src-induced phosphorylation of caveolin-2 on tyrosine 19. Phospho-caveolin-2 (Tyr(P)19) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

A Src family kinase-Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05480&geneProductId=UniProtKB:P05480

signaling receptor binding

ISO

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

extrinsic component of cytoplasmic side of plasma membrane

cell component

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

1 reference

9 May 2019

The membrane targeting and spatial activation of Src, Yes and Fyn is influenced by palmitoylation and distinct RhoB/RhoD endosome requirements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

1 reference

9 May 2019

The membrane targeting and spatial activation of Src, Yes and Fyn is influenced by palmitoylation and distinct RhoB/RhoD endosome requirements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

mitochondrial inner membrane

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Src-induced phosphorylation of caveolin-2 on tyrosine 19. Phospho-caveolin-2 (Tyr(P)19) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

1 reference

9 May 2019

Src-dependent phosphorylation of ASAP1 regulates podosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Regulation of connexin43 protein complexes by intracellular acidification

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

The guanine nucleotide exchange factor Arhgef5 plays crucial roles in Src-induced podosome formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

perinuclear region of cytoplasm

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Mechanical loading in osteocytes induces formation of a Src/Pyk2/MBD2 complex that suppresses anabolic gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

The membrane targeting and spatial activation of Src, Yes and Fyn is influenced by palmitoylation and distinct RhoB/RhoD endosome requirements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

TAS

glutamatergic synapse

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05480&geneProductId=UniProtKB:P05480

postsynaptic specialization, intracellular component

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05480&geneProductId=UniProtKB:P05480

response to mineralocorticoid

biological process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

positive regulation of canonical Wnt signaling pathway

1 reference

9 May 2019

Dishevelled-2 docks and activates Src in a Wnt-dependent manner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

regulation of intracellular estrogen receptor signaling pathway

1 reference

9 May 2019

c-Src-null mice exhibit defects in normal mammary gland development and ERalpha signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

substrate adhesion-dependent cell spreading

1 reference

9 May 2019

Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

Targeted disruption of leucine-rich repeat kinase 1 but not leucine-rich repeat kinase 2 in mice causes severe osteopetrosis

osteoclast development

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05480&geneProductId=UniProtKB:P05480

cellular response to hypoxia

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

cellular response to transforming growth factor beta stimulus

1 reference

9 May 2019

Redox-induced Src kinase and caveolin-1 signaling in TGF-β1-initiated SMAD2/3 activation and PAI-1 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

branching involved in mammary gland duct morphogenesis

1 reference

9 May 2019

c-Src-null mice exhibit defects in normal mammary gland development and ERalpha signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

response to mechanical stimulus

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

1 reference

16 July 2018

Src kinase activity is essential for osteoclast function

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05480&geneProductId=UniProtKB:P05480

positive regulation of platelet-derived growth factor receptor signaling pathway

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

1 reference

9 May 2019

c-Src-null mice exhibit defects in normal mammary gland development and ERalpha signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

response to nutrient levels

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

positive regulation of protein processing

1 reference

9 May 2019

The transcriptional repressor Glis2 is a novel binding partner for p120 catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

cellular response to insulin stimulus

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

positive regulation of peptidyl-tyrosine phosphorylation

1 reference

9 May 2019

The transcriptional repressor Glis2 is a novel binding partner for p120 catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05480&geneProductId=UniProtKB:P05480

innate immune response

1 reference

16 July 2018

response to acidic pH

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

response to fatty acid

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

regulation of cell projection assembly

1 reference

9 May 2019

Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

immune system process

1 reference

9 May 2019

cellular response to platelet-derived growth factor stimulus

1 reference

9 May 2019

The membrane targeting and spatial activation of Src, Yes and Fyn is influenced by palmitoylation and distinct RhoB/RhoD endosome requirements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

cellular response to fluid shear stress

1 reference

9 May 2019

Mechanical loading in osteocytes induces formation of a Src/Pyk2/MBD2 complex that suppresses anabolic gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

response to electrical stimulus

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

1 reference

9 May 2019

c-Src-null mice exhibit defects in normal mammary gland development and ERalpha signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

Genetic disruption of the sh3pxd2a gene reveals an essential role in mouse development and the existence of a novel isoform of tks5

protein destabilization

1 reference

9 May 2019

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

peptidyl-tyrosine autophosphorylation

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

response to hydrogen peroxide

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

positive regulation of protein localization to nucleus

1 reference

9 May 2019

The transcriptional repressor Glis2 is a novel binding partner for p120 catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05480&geneProductId=UniProtKB:P05480

regulation of cell cycle

1 reference

16 July 2018

cellular response to reactive oxygen species

1 reference

9 May 2019

A reactive oxygen species-mediated, self-perpetuating loop persistently activates platelet-derived growth factor receptor α

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

cellular response to peptide hormone stimulus

1 reference

9 May 2019

Caveolin-1 modulates cardiac gap junction homeostasis and arrhythmogenecity by regulating cSrc tyrosine kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

cellular response to fatty acid

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

regulation of cell population proliferation

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05480&geneProductId=UniProtKB:P05480

angiotensin-activated signaling pathway involved in heart process

1 reference

9 May 2019

Caveolin-1 modulates cardiac gap junction homeostasis and arrhythmogenecity by regulating cSrc tyrosine kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

Absence of Fyn and Src causes a reeler-like phenotype

forebrain development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

regulation of protein binding

1 reference

9 May 2019

Role of scaffold protein afadin dilute domain-interacting protein (ADIP) in platelet-derived growth factor-induced cell movement by activating Rac protein through Vav2 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

cellular response to lipopolysaccharide

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

1 reference

9 May 2019

Alterations in cell-adhesive and migratory properties of proximal tubule and collecting duct cells from bcl-2 -/- mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

negative regulation of intrinsic apoptotic signaling pathway

peptidyl-tyrosine phosphorylation

3 references

9 May 2019

Interchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Reelin activates SRC family tyrosine kinases in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

protein phosphorylation

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

A role for mitogen-activated protein kinase(Erk1/2) activation and non-selective pore formation in P2X7 receptor-mediated thymocyte death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

intracellular signal transduction

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Targeted disruption of leucine-rich repeat kinase 1 but not leucine-rich repeat kinase 2 in mice causes severe osteopetrosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

negative regulation of extrinsic apoptotic signaling pathway

positive regulation of podosome assembly

3 references

9 May 2019

The guanine nucleotide exchange factor Arhgef5 plays crucial roles in Src-induced podosome formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

The guanine nucleotide exchange factor Arhgef5 plays crucial roles in Src-induced podosome formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Phosphorylation of moesin by Jun N-terminal kinase is important for podosome rosette formation in Src-transformed fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

platelet-derived growth factor receptor signaling pathway

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05480&geneProductId=UniProtKB:P05480

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

progesterone receptor signaling pathway

positive regulation of ERK1 and ERK2 cascade

3 references

regulation of postsynaptic neurotransmitter receptor activity

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05480&geneProductId=UniProtKB:P05480

transmembrane receptor protein tyrosine kinase signaling pathway

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

3 references

9 May 2019

Src kinase activity is essential for osteoclast function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Impaired gastric acidification negatively affects calcium homeostasis and bone mass.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

cellular response to hydrogen peroxide

1 reference

9 May 2019

A signaling cascade mediated by ceramide, src and PDGFRβ coordinates the activation of the redox-sensitive neutral sphingomyelinase-2 and sphingosine kinase-1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

positive regulation of platelet-derived growth factor receptor-beta signaling pathway

1 reference

9 May 2019

A signaling cascade mediated by ceramide, src and PDGFRβ coordinates the activation of the redox-sensitive neutral sphingomyelinase-2 and sphingosine kinase-1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

1 reference

9 May 2019

Osteopetrosis, osteopetrorickets and hypophosphatemic rickets differentially affect dentin and enamel mineralization.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05480

1 reference

tyrosine-protein kinase, catalytic domain

1 reference

tyrosine-protein kinase, active site

1 reference

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

SH3 domain

1 reference

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference