(Q21985076)

English

Jagged 2

mammalian protein found in Mus musculus

syndactylism
Jag2
protein jagged-2

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

Protein jagged-2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QYE5

Growth factor receptor cysteine-rich domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QYE5

membrane proteins

1 reference

based on heuristic

inferred from GOA cell component → membrane

VWFC domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Notch ligand, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Delta/Serrate/lag-2 (DSL) protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like calcium-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like calcium-binding, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

calcium ion binding

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

14 February 2019

Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

growth factor activity

determination method

3 references

9 May 2019

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

determination method

5 references

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

9 May 2019

Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

determination method

plasma membrane

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

integral component of plasma membrane

determination method

1 reference

9 May 2019

Mouse Jagged2 is differentially expressed in hematopoietic progenitors and endothelial cells and promotes the survival and proliferation of hematopoietic progenitors by direct cell-to-cell contact

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

perinuclear region of cytoplasm

determination method

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

biological process

skeletal system development

determination method

1 reference

9 May 2019

Role of the Notch signalling pathway in tooth morphogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

respiratory system process

determination method

1 reference

9 May 2019

Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

epithelial cell apoptotic process involved in palatal shelf morphogenesis

determination method

1 reference

9 May 2019

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

in utero embryonic development

determination method

1 reference

9 May 2019

Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

sensory perception of sound

determination method

1 reference

9 May 2019

Notch signalling pathway mediates hair cell development in mammalian cochlea

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

odontogenesis of dentin-containing tooth

determination method

1 reference

9 May 2019

Role of the Notch signalling pathway in tooth morphogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

cell communication

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

auditory receptor cell fate commitment

determination method

1 reference

9 May 2019

Notch signalling pathway mediates hair cell development in mammalian cochlea

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

regulation of cell adhesion

determination method

1 reference

9 May 2019

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

regulation of cell population proliferation

determination method

3 references

9 May 2019

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

cell fate determination

determination method

1 reference

9 May 2019

Mouse Jagged2 is differentially expressed in hematopoietic progenitors and endothelial cells and promotes the survival and proliferation of hematopoietic progenitors by direct cell-to-cell contact

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

morphogenesis of embryonic epithelium

determination method

1 reference

9 May 2019

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

gamma-delta T cell differentiation

determination method

1 reference

9 May 2019

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

thymic T cell selection

determination method

3 references

9 May 2019

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

positive regulation of Notch signaling pathway

determination method

1 reference

9 May 2019

Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

regulation of signaling receptor activity

determination method

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

negative regulation of Notch signaling pathway

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYE5

determination method

EGF-like calcium-binding, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QYE5

Notch ligand, N-terminal domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QYE5

EGF-like calcium-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QYE5

EGF-like, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QYE5

Delta/Serrate/lag-2 (DSL) protein

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QYE5

EGF-type aspartate/asparagine hydroxylation site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QYE5

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QYE5

EGF-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QYE5

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000075224

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000075224

ENSMUSP00000152342

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000152342

Sitelinks

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Wikisource(0 entries)

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Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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