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English
Acid phosphatase 2, lysosomal
mammalian protein found in Mus musculus
lysosomal acid phosphatase
Acp2
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P24638
part of
Histidine phosphatase superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P24638
Histidine phosphatase superfamily, clade-2
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P24638
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
Histidine acid phosphatase active site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P24638
encoded by
Acp2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P24638
molecular function
hydrolase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P24638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IEA
phosphotyrosine residue binding
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
ISO
acid phosphatase activity
determination method
IDA
IEA
IMP
ISO
8 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
ISO
retrieved
14 February 2019
stated in
Mice deficient in lysosomal acid phosphatase develop lysosomal storage in the kidney and central nervous system
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IMP
retrieved
14 February 2019
stated in
Overlapping functions of lysosomal acid phosphatase (LAP) and tartrate-resistant acid phosphatase (Acp5) revealed by doubly deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IMP
retrieved
14 February 2019
stated in
Mutation in the gene encoding lysosomal acid phosphatase (Acp2) causes cerebellum and skin malformation in mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IMP
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P24638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IEA
retrieved
14 February 2019
stated in
Confirmational, provisional, and/or regional assignment of 15 enzyme loci onto Chinese hamster autosomes 1, 2, and 7
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IDA
retrieved
14 February 2019
stated in
Chromosomal assignments of 23 biochemical loci of the rat by using rat x mouse somatic cell hybrids
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IDA
retrieved
14 February 2019
stated in
Mice lacking tartrate-resistant acid phosphatase (Acp 5) have disordered macrophage inflammatory responses and reduced clearance of the pathogen, Staphylococcus aureus
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IDA
phosphoprotein phosphatase activity
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
ISO
cell component
integral component of membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P24638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IEA
lysosomal membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P24638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IEA
lysosome
determination method
IDA
IEA
IMP
ISO
5 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
ISO
retrieved
14 February 2019
stated in
Overlapping functions of lysosomal acid phosphatase (LAP) and tartrate-resistant acid phosphatase (Acp5) revealed by doubly deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IMP
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P24638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IEA
retrieved
14 February 2019
stated in
Mice lacking tartrate-resistant acid phosphatase (Acp 5) have disordered macrophage inflammatory responses and reduced clearance of the pathogen, Staphylococcus aureus
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IDA
lysosomal lumen
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P24638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P24638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IEA
cytoplasmic vesicle
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
ISO
neuron projection
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
ISO
biological process
skeletal system development
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Mice deficient in lysosomal acid phosphatase develop lysosomal storage in the kidney and central nervous system
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IMP
lysosome organization
determination method
IMP
2 references
retrieved
14 February 2019
stated in
Mice deficient in lysosomal acid phosphatase develop lysosomal storage in the kidney and central nervous system
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IMP
retrieved
14 February 2019
stated in
Conditional overexpression of active transforming growth factor beta1 in vivo accelerates metastases of transgenic mammary tumors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IMP
dephosphorylation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IEA
protein dephosphorylation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
IEA
response to organic substance
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
ISO
autophagic cell death
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24638
determination method
ISO
has part(s)
Histidine acid phosphatase active site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P24638
Identifiers
RefSeq protein ID
NP_031413
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
11432
XP_011237559
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
11432
NP_001343996
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
11432
UniProt protein ID
P24638
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P24638
Ensembl protein ID
ENSMUSP00000002172
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000002172
ENSMUSP00000116030
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000116030
ENSMUSP00000119144
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000119144
ENSMUSP00000159053
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000159053
ENSMUSP00000159089
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000159089
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