(Q21985658)

http://www.ebi.ac.uk/interpro/protein/Q99JW4

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Zinc finger, LIM-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

protein kinase binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

perinuclear region of cytoplasm

cell component

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

14 February 2019

PINCH2 is a new five LIM domain protein, homologous to PINCHand localized to focal adhesions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

14 February 2019

Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

protein-containing complex

IDA

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

9 May 2019

Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

9 May 2019

PINCH2 is a new five LIM domain protein, homologous to PINCHand localized to focal adhesions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

establishment of protein localization

IBA

biological process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

positive regulation of substrate adhesion-dependent cell spreading

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

1 reference

9 May 2019

PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

positive regulation of focal adhesion assembly

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

positive regulation of GTPase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

cell-cell junction organization

1 reference

14 February 2019

Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

establishment or maintenance of cell polarity

1 reference

9 May 2019

PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

negative regulation of epithelial cell proliferation

1 reference

9 May 2019

Role of PINCH and its partner tumor suppressor Rsu-1 in regulating liver size and tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

positive regulation of gene expression

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

positive regulation of integrin-mediated signaling pathway

1 reference

14 February 2019

Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

positive regulation of cell-substrate adhesion

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

negative regulation of neural precursor cell proliferation

1 reference

9 May 2019

Dissecting integrin-dependent regulation of neural stem cell proliferation in the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

negative regulation of hepatocyte proliferation

1 reference

9 May 2019

Role of PINCH and its partner tumor suppressor Rsu-1 in regulating liver size and tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

negative regulation of transcription, DNA-templated

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

chordate embryonic development

1 reference

9 May 2019

PINCH1 plays an essential role in early murine embryonic development but is dispensable in ventricular cardiomyocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

negative regulation of apoptotic process

1 reference

9 May 2019

Role of PINCH and its partner tumor suppressor Rsu-1 in regulating liver size and tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

tumor necrosis factor-mediated signaling pathway

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

positive regulation of NIK/NF-kappaB signaling

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

1 reference

14 February 2019

PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

protein heterooligomerization

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99JW4

positive regulation of integrin-mediated signaling pathway

Zinc finger, LIM-type

1 reference

stated in

InterPro Release 71.0