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(Q21986472)
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Kinase suppressor of ras 2
mammalian protein found in Mus musculus
testes-kinase suppressor of ras 2 isoform
Ksr2
kinase suppressor of Ras 2
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q3UVC0
part of
Protein kinase-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q3UVC0
Kinase suppressor of RAS, SAM-like domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q3UVC0
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Protein kinase domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Serine/threonine-protein kinase, active site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q3UVC0
encoded by
Ksr2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q3UVC0
molecular function
transferase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q3UVC0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IEA
nucleotide binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q3UVC0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IEA
protein serine/threonine kinase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q3UVC0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IEA
mitogen-activated protein kinase kinase binding
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IDA
protein binding
determination method
IPI
1 reference
retrieved
14 February 2019
stated in
KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IPI
ATP binding
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q3UVC0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IEA
MAP-kinase scaffold activity
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IDA
metal ion binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q3UVC0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IEA
kinase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q3UVC0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IEA
protein kinase activity
determination method
IBA
IEA
2 references
retrieved
27 March 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UVC0&geneProductId=UniProtKB:Q3UVC0
determination method
IEA
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UVC0&geneProductId=UniProtKB:Q3UVC0
determination method
IBA
signal transducer activity
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UVC0&geneProductId=UniProtKB:Q3UVC0
determination method
IBA
protein kinase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IEA
cell component
cytoplasm
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q3UVC0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IEA
cytosol
determination method
IDA
1 reference
retrieved
27 March 2018
stated in
KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UVC0&geneProductId=UniProtKB:Q3UVC0
determination method
IDA
plasma membrane
determination method
IDA
1 reference
retrieved
27 March 2018
stated in
KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UVC0&geneProductId=UniProtKB:Q3UVC0
determination method
IDA
membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q3UVC0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IEA
cytosol
determination method
IBA
IDA
2 references
retrieved
14 February 2019
stated in
KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IBA
plasma membrane
determination method
IBA
IDA
2 references
retrieved
14 February 2019
stated in
KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IBA
biological process
protein phosphorylation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IEA
intracellular signal transduction
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IEA
phosphorylation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q3UVC0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IEA
calcium-mediated signaling
determination method
IGI
1 reference
retrieved
27 March 2018
stated in
KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UVC0&geneProductId=UniProtKB:Q3UVC0
determination method
IGI
positive regulation of MAPK cascade
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IDA
Ras protein signal transduction
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IBA
calcium-mediated signaling
determination method
IBA
IGI
2 references
retrieved
14 February 2019
stated in
KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IGI
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IBA
positive regulation of cold-induced thermogenesis
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Kinase Suppressor of Ras 2 (KSR2) expression in the brain regulates energy balance and glucose homeostasis.
GOA
curator
YuBioLab
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UVC0
determination method
IMP
has part(s)
serine/threonine-protein kinase, active site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q3UVC0
serine-threonine/tyrosine-protein kinase, catalytic domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q3UVC0
protein kinase C-like, phorbol ester/diacylglycerol-binding domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q3UVC0
protein kinase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q3UVC0
Identifiers
RefSeq protein ID
NP_001299843
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
333050
XP_006530456
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
333050
XP_006530457
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
333050
XP_006530458
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
333050
UniProt protein ID
Q3UVC0
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q3UVC0
Ensembl protein ID
ENSMUSP00000137670
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000137670
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