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(Q21986578)
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Myosin regulatory light chain interacting protein
mammalian protein found in Mus musculus
Mylip
Myosin regulatory light chain-interacting protein
inducible degrader of the LDL-receptor
RING-type E3 ubiquitin transferase MYLIP
idol
E3 ubiquitin-protein ligase MYLIP
MIR
In more languages
default for all languages
No label defined
No description defined
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8BM54
part of
Ubiquitin-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8BM54
Zinc finger, RING/FYVE/PHD-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8BM54
Ezrin/radixin/moesin-like
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8BM54
FERM/acyl-CoA-binding protein superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8BM54
PH-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8BM54
FERM superfamily, second domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8BM54
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
Band 4.1 domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Zinc finger, RING-type, protein family
1 reference
based on heuristic
inferred from protein domain or family
FERM central domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
FERM, C-terminal PH-like domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
FERM, N-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
FERM domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8BM54
encoded by
Mylip
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8BM54
molecular function
ubiquitin protein ligase activity
determination method
IEA
IMP
ISO
3 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
ISO
retrieved
14 February 2019
stated in
LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IMP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IEA
metal ion binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8BM54
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IEA
ubiquitin-protein transferase activity
determination method
IEA
IMP
ISO
3 references
retrieved
16 July 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BM54&geneProductId=UniProtKB:Q8BM54
determination method
ISO
retrieved
16 July 2018
stated in
LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor
GOA
curator
UniProt
UniProt protein ID
Q8BM54
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BM54&geneProductId=UniProtKB:Q8BM54
determination method
IMP
retrieved
16 July 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BM54&geneProductId=UniProtKB:Q8BM54
determination method
IEA
cytoskeletal protein binding
determination method
IEA
ISO
3 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IEA
structural constituent of cytoskeleton
determination method
IBA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BM54&geneProductId=UniProtKB:Q8BM54
determination method
IBA
transferase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8BM54
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IEA
ubiquitin-protein transferase activity
determination method
IBA
IEA
IMP
ISO
4 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
ISO
retrieved
14 February 2019
stated in
LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor
GOA
curator
UniProt
UniProt protein ID
Q8BM54
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IMP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IBA
cell component
cytoplasm
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8BM54
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8BM54
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IEA
plasma membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8BM54
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IEA
intracellular anatomical structure
determination method
IEA
ISO
2 references
retrieved
10 September 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BM54&geneProductId=UniProtKB:Q8BM54
determination method
ISO
retrieved
10 September 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BM54&geneProductId=UniProtKB:Q8BM54
determination method
IEA
cytoskeleton
determination method
IBA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BM54&geneProductId=UniProtKB:Q8BM54
determination method
IBA
cytoskeleton
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IEA
biological process
positive regulation of protein catabolic process
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IDA
negative regulation of low-density lipoprotein particle clearance
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IDA
regulation of low-density lipoprotein particle receptor catabolic process
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IMP
nervous system development
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IEA
protein destabilization
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IDA
cholesterol homeostasis
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IMP
actomyosin structure organization
determination method
IBA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BM54&geneProductId=UniProtKB:Q8BM54
determination method
IBA
protein ubiquitination
determination method
IEA
ISO
3 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8BM54
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IEA
cellular response to low-density lipoprotein particle stimulus
determination method
IC
1 reference
retrieved
14 February 2019
stated in
LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IC
ubiquitin-dependent protein catabolic process
determination method
IDA
1 reference
retrieved
16 July 2018
stated in
LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BM54&geneProductId=UniProtKB:Q8BM54
determination method
IDA
negative regulation of neuron projection development
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IEA
cytoskeleton organization
determination method
IEA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BM54&geneProductId=UniProtKB:Q8BM54
determination method
IEA
ubiquitin-dependent protein catabolic process
determination method
IBA
IDA
2 references
retrieved
14 February 2019
stated in
LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BM54
determination method
IBA
has part(s)
FERM domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8BM54
Zinc finger, RING-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8BM54
FERM central domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8BM54
FERM, C-terminal PH-like domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8BM54
Band 4.1 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8BM54
FERM, N-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8BM54
Identifiers
RefSeq protein ID
NP_722484
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
218203
XP_036013884
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
218203
UniProt protein ID
Q8BM54
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8BM54
Ensembl protein ID
ENSMUSP00000047403
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000047403
ENSMUSP00000152597
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000152597
Sitelinks
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Wikiquote
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