(Q21986780)

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6PD21&geneProductId=UniProtKB:Q6PD21

1 reference

14 February 2019

Shb is a ubiquitously expressed Src homology 2 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

cytoplasmic ribonucleoprotein granule

ISO

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

multicellular organism development

ISO

biological process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

positive regulation of T-helper cell differentiation

IEA

1 reference

14 February 2019

Absence of the adaptor protein Shb potentiates the T helper type 2 response in a mouse model of atopic dermatitis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

hematopoietic stem cell proliferation

1 reference

14 February 2019

The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

1 reference

14 February 2019

Dual role of the tyrosine kinase GTK and the adaptor protein SHB in beta-cell growth: enhanced beta-cell replication after 60% pancreatectomy and increased sensitivity to streptozotocin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

positive regulation of mitotic cell cycle

IDA

1 reference

14 February 2019

The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth

blood vessel development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

T cell receptor signaling pathway

1 reference

14 February 2019

Absence of the adaptor protein Shb potentiates the T helper type 2 response in a mouse model of atopic dermatitis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

blood vessel morphogenesis

2 references

14 February 2019

Shb promotes blood vessel formation in embryoid bodies by augmenting vascular endothelial growth factor receptor-2 and platelet-derived growth factor receptor-beta signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

14 February 2019

Shb promotes blood vessel formation in embryoid bodies by augmenting vascular endothelial growth factor receptor-2 and platelet-derived growth factor receptor-beta signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

negative regulation of protein kinase activity

IEA

1 reference

14 February 2019

The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

negative regulation of oocyte maturation

1 reference

14 February 2019

The Src homology 2 domain-containing adapter protein B (SHB) regulates mouse oocyte maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

positive regulation of signal transduction

IEA

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

1 reference

14 February 2019

The SHB adapter protein is required for normal maturation of mesoderm during in vitro differentiation of embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PD21

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6PD21

SHB, SH2 domain

1 reference

stated in

InterPro Release 71.0