(Q21986790)

English

Shroom family member 2

mammalian protein found in Mus musculus

Shroom2
Protein Apxl
protein Shroom2

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/A2ALU4

PDZ superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/A2ALU4

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Apx/Shrm Domain 1, protein family

1 reference

based on heuristic

inferred from protein domain or family

Apx/Shrm Domain 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

PDZ domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

beta-catenin binding

determination method

1 reference

14 February 2019

Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

protein domain specific binding

determination method

1 reference

14 February 2019

Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

actin filament binding

determination method

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2ALU4&geneProductId=UniProtKB:A2ALU4

determination method

21 June 2018

Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2ALU4&geneProductId=UniProtKB:A2ALU4

determination method

21 June 2018

Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2ALU4&geneProductId=UniProtKB:A2ALU4

determination method

protein binding

determination method

1 reference

14 February 2019

Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

actin filament binding

determination method

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

14 February 2019

Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

14 February 2019

Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

filamentous actin

determination method

1 reference

31 January 2018

Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2ALU4&geneProductId=UniProtKB:A2ALU4

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

cell-cell junction

determination method

1 reference

14 February 2019

Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

neuronal cell body

determination method

1 reference

14 February 2019

Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

determination method

1 reference

14 February 2019

Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

apical plasma membrane

determination method

3 references

21 June 2018

Shroom2 (APXL) regulates melanosome biogenesis and localization in the retinal pigment epithelium

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2ALU4&geneProductId=UniProtKB:A2ALU4

determination method

21 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2ALU4&geneProductId=UniProtKB:A2ALU4

determination method

21 June 2018

Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2ALU4&geneProductId=UniProtKB:A2ALU4

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

apical junction complex

determination method

1 reference

21 June 2018

Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2ALU4&geneProductId=UniProtKB:A2ALU4

determination method

adherens junction

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

apical plasma membrane

determination method

4 references

14 February 2019

Shroom2 (APXL) regulates melanosome biogenesis and localization in the retinal pigment epithelium

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

14 February 2019

Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

cortical actin cytoskeleton

determination method

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

14 February 2019

Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

biological process

eye pigment granule organization

determination method

1 reference

14 February 2019

Shroom2 (APXL) regulates melanosome biogenesis and localization in the retinal pigment epithelium

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

ear development

determination method

1 reference

14 February 2019

Shroom2 (APXL) regulates melanosome biogenesis and localization in the retinal pigment epithelium

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

negative regulation of actin filament depolymerization

determination method

1 reference

14 February 2019

Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

actin filament bundle assembly

determination method

1 reference

14 February 2019

Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

multicellular organism development

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

melanosome organization

determination method

1 reference

14 February 2019

Shroom2 (APXL) regulates melanosome biogenesis and localization in the retinal pigment epithelium

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

brain development

determination method

1 reference

14 February 2019

Shroom2 (APXL) regulates melanosome biogenesis and localization in the retinal pigment epithelium

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

cell-cell junction maintenance

determination method

1 reference

14 February 2019

Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

lens morphogenesis in camera-type eye

determination method

1 reference

14 February 2019

Shroom2 (APXL) regulates melanosome biogenesis and localization in the retinal pigment epithelium

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

cell morphogenesis

determination method

1 reference

14 February 2019

Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

camera-type eye development

determination method

1 reference

14 February 2019

Shroom2 (APXL) regulates melanosome biogenesis and localization in the retinal pigment epithelium

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

cellular pigment accumulation

determination method

1 reference

14 February 2019

Shroom2 (APXL) regulates melanosome biogenesis and localization in the retinal pigment epithelium

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

determination method

1 reference

14 February 2019

Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

camera-type eye morphogenesis

determination method

1 reference

14 February 2019

Shroom2 (APXL) regulates melanosome biogenesis and localization in the retinal pigment epithelium

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

actin filament organization

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

actin cytoskeleton organization

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2ALU4

determination method

Apx/Shrm Domain 2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/A2ALU4

Apx/Shrm Domain 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/A2ALU4

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/A2ALU4

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000057500

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000057500

ENSMUSP00000098701

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000098701

Sitelinks

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Wiktionary(0 entries)

Multilingual sites(0 entries)

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