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(Q21987157)
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Lymphocyte-activation gene 3
mammalian protein found in Mus musculus
Lag3
aida
activation-induced cytidine deaminase-linked autoimmunity protein
lymphocyte activation gene 3 protein
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q61790
part of
interleukin-1 receptor family
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61790
Immunoglobulin-like fold
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61790
Immunoglobulin-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61790
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
Immunoglobulin subtype, protein family
1 reference
based on heuristic
inferred from protein domain or family
immunoglobulin-like domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Immunoglobulin domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q61790
encoded by
Lag3
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q61790
molecular function
transmembrane signaling receptor activity
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Cutting edge: molecular analysis of the negative regulatory function of lymphocyte activation gene-3
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61790
determination method
IDA
MHC class II protein binding
determination method
IDA
IEA
ISO
3 references
retrieved
14 February 2019
stated in
Characterization of the major histocompatibility complex class II binding site on LAG-3 protein
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61790
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61790
determination method
IEA
retrieved
14 February 2019
stated in
Cutting edge: molecular analysis of the negative regulatory function of lymphocyte activation gene-3
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61790
determination method
IDA
cell component
integral component of membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61790
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61790
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61790
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61790
determination method
IEA
external side of plasma membrane
determination method
IDA
2 references
retrieved
14 February 2019
stated in
Independent modes of natural killing distinguished in mice lacking Lag3
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61790
determination method
IDA
retrieved
14 February 2019
stated in
Cutting edge: molecular analysis of the negative regulatory function of lymphocyte activation gene-3
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61790
determination method
IDA
biological process
cell surface receptor signaling pathway
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Cutting edge: molecular analysis of the negative regulatory function of lymphocyte activation gene-3
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61790
determination method
IDA
negative regulation of T cell activation
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Cutting edge: molecular analysis of the negative regulatory function of lymphocyte activation gene-3
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61790
determination method
IDA
positive regulation of natural killer cell mediated cytotoxicity
determination method
IDA
IMP
2 references
retrieved
14 February 2019
stated in
Independent modes of natural killing distinguished in mice lacking Lag3
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61790
determination method
IMP
retrieved
14 February 2019
stated in
Independent modes of natural killing distinguished in mice lacking Lag3
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61790
determination method
IDA
has part(s)
immunoglobulin subtype
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61790
immunoglobulin domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61790
immunoglobulin-like domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61790
Identifiers
RefSeq protein ID
NP_032505
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
16768
UniProt protein ID
Q61790
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q61790
Ensembl protein ID
ENSMUSP00000032217
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000032217
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