Wikidata

(Q21987757)

English

Nuclear factor of activated T-cells, cytoplasmic 1

mouse protein (annotated by UniProtKB/Swiss-Prot O88942)

  • NFAT transcription complex cytosolic component
  • NF-ATc
  • NFATc
In more languages

Statements

instance of
protein
0 references
molecular function
DNA-binding transcription activator activity, RNA polymerase II-specific
determination method
IDA
4 references
retrieved
10 September 2018
stated in
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
10 September 2018
stated in
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
cell component
cytoplasm
determination method
IDA
IEA
7 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88942
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IEA
retrieved
14 February 2019
stated in
Nf1 has an essential role in endothelial cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Inositol polyphosphate 4-phosphatase B as a regulator of bone mass in mice and humans
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Defective T cell development and function in calcineurin A beta -deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
NFATc1 mediates HDAC-dependent transcriptional repression of osteocalcin expression during osteoblast differentiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Loss of connexin45 causes a cushion defect in early cardiogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
nucleus
determination method
IDA
IEA
ISO
17 references
retrieved
21 June 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
ISO
retrieved
21 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O88942
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IEA
retrieved
21 June 2018
stated in
Tmem178 acts in a novel negative feedback loop targeting NFATc1 to regulate bone mass
GOA
curator
UniProt
UniProt protein ID
O88942
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
Fibrillin-1 directly regulates osteoclast formation and function by a dual mechanism
GOA
curator
UniProt
UniProt protein ID
O88942
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
NFATc1 balances quiescence and proliferation of skin stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
Dysregulation of connexins and inactivation of NFATc1 in the cardiovascular system of Nkx2-5 null mutants
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
The transcription factor NF-ATc is essential for cardiac valve formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
Overexpression of TEAD-1 in transgenic mouse striated muscles produces a slower skeletal muscle contractile phenotype
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
Inositol polyphosphate 4-phosphatase B as a regulator of bone mass in mice and humans
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
Regulation of mature T lymphocyte proliferation and differentiation by Par-4
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
NFATc1 regulates lymphatic endothelial development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
NFATc1 mediates HDAC-dependent transcriptional repression of osteocalcin expression during osteoblast differentiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
Loss of connexin45 causes a cushion defect in early cardiogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
nucleus
determination method
IBA
IDA
IEA
ISO
18 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88942
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IEA
retrieved
14 February 2019
stated in
Fibrillin-1 directly regulates osteoclast formation and function by a dual mechanism
GOA
curator
UniProt
UniProt protein ID
O88942
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Tmem178 acts in a novel negative feedback loop targeting NFATc1 to regulate bone mass
GOA
curator
UniProt
UniProt protein ID
O88942
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Regulation of mature T lymphocyte proliferation and differentiation by Par-4
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Inositol polyphosphate 4-phosphatase B as a regulator of bone mass in mice and humans
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
The transcription factor NF-ATc is essential for cardiac valve formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
NFATc1 regulates lymphatic endothelial development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
NFATc1 balances quiescence and proliferation of skin stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
NFATc1 mediates HDAC-dependent transcriptional repression of osteocalcin expression during osteoblast differentiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Dysregulation of connexins and inactivation of NFATc1 in the cardiovascular system of Nkx2-5 null mutants
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Overexpression of TEAD-1 in transgenic mouse striated muscles produces a slower skeletal muscle contractile phenotype
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Loss of connexin45 causes a cushion defect in early cardiogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IBA
biological process
positive regulation of transcription by RNA polymerase II
determination method
IDA
ISO
7 references
retrieved
21 June 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
ISO
retrieved
21 June 2018
stated in
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
Protein inhibitor of activated STAT 3 modulates osteoclastogenesis by down-regulation of NFATc1 and osteoclast-associated receptor
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
NFATc1 regulates lymphatic endothelial development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
Expression of utrophin A mRNA correlates with the oxidative capacity of skeletal muscle fiber types and is regulated by calcineurin/NFAT signaling
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
Scleraxis and NFATc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
21 June 2018
stated in
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88942&geneProductId=UniProtKB:O88942
determination method
IDA
positive regulation of transcription by RNA polymerase II
determination method
IBA
IDA
ISO
8 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
ISO
retrieved
14 February 2019
stated in
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
NFATc1 regulates lymphatic endothelial development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Protein inhibitor of activated STAT 3 modulates osteoclastogenesis by down-regulation of NFATc1 and osteoclast-associated receptor
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Scleraxis and NFATc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Expression of utrophin A mRNA correlates with the oxidative capacity of skeletal muscle fiber types and is regulated by calcineurin/NFAT signaling
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88942
determination method
IBA

Identifiers

 
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