(Q21987813)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8K2T8

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

1 reference

25 May 2022

1 reference

25 May 2022

RNA polymerase II complex binding

3 references

1 reference

27 March 2018

Dynamic loss of H2B ubiquitylation without corresponding changes in H3K4 trimethylation during myogenic differentiation

GOA

curator

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K2T8&geneProductId=UniProtKB:Q8K2T8

protein binding

RNA polymerase II complex binding

IPI

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2T8

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2T8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2T8

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2T8

IBA

chromatin binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K2T8&geneProductId=UniProtKB:Q8K2T8

4 references

27 March 2018

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K2T8&geneProductId=UniProtKB:Q8K2T8

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K2T8&geneProductId=UniProtKB:Q8K2T8

27 March 2018

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K2T8&geneProductId=UniProtKB:Q8K2T8

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2T8

1 reference

14 February 2019

Cdc73/Paf1 complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K2T8&geneProductId=UniProtKB:Q8K2T8

5 references

10 September 2018

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K2T8&geneProductId=UniProtKB:Q8K2T8

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K2T8&geneProductId=UniProtKB:Q8K2T8

10 September 2018

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K2T8&geneProductId=UniProtKB:Q8K2T8

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K2T8&geneProductId=UniProtKB:Q8K2T8

IBA

Cdc73/Paf1 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2T8

6 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2T8

14 February 2019

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2T8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2T8

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2T8

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2T8

regulation of transcription, DNA-templated

IBA

biological process

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K2T8&geneProductId=UniProtKB:Q8K2T8

1 reference

27 March 2018

positive regulation of mRNA 3'-end processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2T8

1 reference

14 February 2019

transcription elongation from RNA polymerase II promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2T8

1 reference

14 February 2019

negative regulation of transcription by RNA polymerase II

1 reference

14 February 2019

A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2T8

Wnt signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2T8

1 reference

14 February 2019

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K2T8&geneProductId=UniProtKB:Q8K2T8

1 reference

27 March 2018

stem cell population maintenance

1 reference

14 February 2019

A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2T8

mRNA polyadenylation

endodermal cell fate commitment

1 reference

14 February 2019

A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2T8

cellular response to lipopolysaccharide

1 reference

14 February 2019

hCTR9, a component of Paf1 complex, participates in the transcription of interleukin 6-responsive genes through regulation of STAT3-DNA interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K2T8

negative regulation of myeloid cell differentiation

positive regulation of transcription elongation from RNA polymerase II promoter

positive regulation of transcription by RNA polymerase II

positive regulation of cell cycle G1/S phase transition