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(Q21987948)
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ELKS/RAB6-interacting/CAST family member 1
mammalian protein found in Mus musculus
ELKS/Rab6-interacting/CAST family member 1
Rab6 interacting protein 2
Erc1
RAB6-interacting protein 2
CAST2
CAZ-associated structural protein 2
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q99MI1
part of
FIP-RBD, C-terminal domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q99MI1
Active zone protein ELKS
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q99MI1
Rab-binding domain FIP-RBD, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q99MI1
encoded by
Erc1
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q99MI1
molecular function
protein binding
determination method
IPI
1 reference
retrieved
9 May 2019
stated in
Characterization of novel Rab6-interacting proteins involved in endosome-to-TGN transport
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IPI
PDZ domain binding
determination method
ISO
ISS
2 references
retrieved
9 May 2019
stated in
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
ISS
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
ISO
cadherin binding
determination method
ISO
1 reference
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99MI1&geneProductId=UniProtKB:Q99MI1
determination method
ISO
structural constituent of presynaptic active zone
determination method
IDA
IMP
2 references
retrieved
9 May 2019
stated in
Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IMP
retrieved
9 May 2019
stated in
Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IDA
voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels
determination method
IDA
IMP
2 references
retrieved
9 May 2019
stated in
The active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neurons
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IMP
retrieved
9 May 2019
stated in
The active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neurons
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IDA
cell component
cytoplasm
determination method
IDA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q99MI1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IEA
retrieved
9 May 2019
stated in
Characterization of novel Rab6-interacting proteins involved in endosome-to-TGN transport
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IDA
presynaptic active zone
determination method
IEA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99MI1&geneProductId=UniProtKB:Q99MI1
determination method
IEA
Golgi membrane
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q99MI1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IEA
Golgi apparatus
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q99MI1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IEA
synapse
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IDA
membrane
determination method
IEA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q99MI1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99MI1&geneProductId=UniProtKB:Q99MI1
determination method
IEA
IkappaB kinase complex
determination method
ISO
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
ISO
synaptic vesicle
determination method
ISO
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
ISO
postsynaptic density
determination method
ISO
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
ISO
membrane
determination method
IEA
ISO
2 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
ISO
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q99MI1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IEA
presynaptic active zone cytoplasmic component
determination method
ISO
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
ISO
glutamatergic synapse
determination method
IDA
IMP
2 references
retrieved
9 May 2019
stated in
ELKS controls the pool of readily releasable vesicles at excitatory synapses through its N-terminal coiled-coil domains.
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IMP
retrieved
9 May 2019
stated in
ELKS controls the pool of readily releasable vesicles at excitatory synapses through its N-terminal coiled-coil domains.
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IDA
GABA-ergic synapse
determination method
IDA
IMP
2 references
retrieved
9 May 2019
stated in
The active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neurons
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IMP
retrieved
9 May 2019
stated in
The active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neurons
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IDA
centrosome
determination method
ISO
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
ISO
microtubule organizing center
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q99MI1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IEA
cytoskeleton
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q99MI1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IEA
ciliary basal body
determination method
ISO
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
ISO
biological process
protein transport
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q99MI1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IEA
retrograde transport, endosome to Golgi
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Characterization of novel Rab6-interacting proteins involved in endosome-to-TGN transport
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IDA
I-kappaB phosphorylation
determination method
ISO
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
ISO
synaptic vesicle priming
determination method
IDA
IMP
2 references
retrieved
9 May 2019
stated in
ELKS controls the pool of readily releasable vesicles at excitatory synapses through its N-terminal coiled-coil domains.
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IMP
retrieved
9 May 2019
stated in
ELKS controls the pool of readily releasable vesicles at excitatory synapses through its N-terminal coiled-coil domains.
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IDA
maintenance of presynaptic active zone structure
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IEA
positive regulation of presynaptic cytosolic calcium concentration
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IEA
induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MI1
determination method
IEA
has part(s)
Rab-binding domain FIP-RBD
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q99MI1
Identifiers
RefSeq protein ID
NP_444434
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
111173
NP_835186
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
111173
XP_006505433
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
111173
XP_006505434
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
111173
XP_006505436
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
111173
XP_006505441
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
111173
XP_030110961
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
111173
XP_030110962
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
111173
XP_030110964
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
111173
XP_030110965
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
111173
XP_030110966
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
111173
XP_030110967
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
111173
XP_030110968
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
111173
XP_030110969
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
111173
XP_030110970
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
111173
XP_036021644
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
111173
UniProt protein ID
Q99MI1
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q99MI1
Ensembl protein ID
ENSMUSP00000078534
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000078534
ENSMUSP00000139030
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000139030
ENSMUSP00000032279
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000032279
ENSMUSP00000138823
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000138823
ENSMUSP00000138989
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000138989
ENSMUSP00000139031
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000139031
ENSMUSP00000139118
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000139118
ENSMUSP00000139152
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000139152
ENSMUSP00000139207
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000139207
ENSMUSP00000139256
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000139256
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