(Q21988152)

Pyridoxal phosphate-dependent transferase domain 1

1 reference

Pyridoxal phosphate-dependent transferase

1 reference

inferred from GOA cell component → membrane

membrane protein

1 reference

based on heuristic

Aminotransferase, class I/classII, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

pyridoxal phosphate binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

acyltransferase activity

1 reference

14 February 2019

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

serine C-palmitoyltransferase activity

serine C-palmitoyltransferase activity

IDA

ISO

2 references

3 references

14 February 2019

ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

14 February 2019

De Novo Sphingolipid Biosynthesis Is Required for Adipocyte Survival and Metabolic Homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

14 February 2019

Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

integral component of membrane

IDA

cell component

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

serine C-palmitoyltransferase complex

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

14 February 2019

A mammalian homolog of the yeast LCB1 encodes a component of serine palmitoyltransferase, the enzyme catalyzing the first step in sphingolipid synthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

14 February 2019

ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

endoplasmic reticulum membrane

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35704&geneProductId=UniProtKB:O35704

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

sphingosine biosynthetic process

endoplasmic reticulum

3 references

1 reference

14 February 2019

Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

sphingomyelin biosynthetic process

IMP

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

sphingolipid metabolic process

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35704&geneProductId=UniProtKB:O35704

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

sphinganine biosynthetic process

1 reference

14 February 2019

Serine palmitoyltransferase (SPT) deficient mice absorb less cholesterol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

ceramide biosynthetic process

IMP

3 references

14 February 2019

ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

14 February 2019

Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

sphingomyelin biosynthetic process

3 references

14 February 2019

A mammalian homolog of the yeast LCB1 encodes a component of serine palmitoyltransferase, the enzyme catalyzing the first step in sphingolipid synthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

14 February 2019

Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

14 February 2019

Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

regulation of fat cell apoptotic process

IDA

1 reference

14 February 2019

De Novo Sphingolipid Biosynthesis Is Required for Adipocyte Survival and Metabolic Homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35704

physically interacts with

IMP

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

6664

language of work or name

English

retrieved

17 August 2016

has part(s)

Aminotransferase, class I/classII

1 reference