(Q21988330)

http://www.ebi.ac.uk/interpro/protein/P70414

CalX-like domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P70414

Sodium/calcium exchanger domain, C-terminal extension, protein family

1 reference

DnaJ domain, protein family

1 reference

Na-Ca exchanger/integrin-beta4, protein family

1 reference

Sodium/calcium exchanger membrane region, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

1 reference

12 September 2018

1 reference

12 September 2018

1 reference

8 April 2019

calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential

ISS

1 reference

8 April 2019

Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

transmembrane transporter binding

TAS

1 reference

8 April 2019

Ankyrin-B regulates Kir6.2 membrane expression and function in heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

calcium:sodium antiporter activity

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

8 April 2019

Targeted disruption of Na+/Ca2+ exchanger gene leads to cardiomyocyte apoptosis and defects in heartbeat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

8 April 2019

Genetic manipulation of cardiac Na+/Ca2+ exchange expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

cytoskeletal protein binding

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

ion antiporter activity involved in regulation of postsynaptic membrane potential

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

integral component of membrane

cell component

intrinsic component of plasma membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

integral component of plasma membrane

ISS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

basolateral plasma membrane

1 reference

8 April 2019

Intrarenal and cellular localization of CLC-K2 protein in the mouse kidney

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

8 April 2019

A novel mutant allele of Ncx1: a single amino acid substitution leads to cardiac dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

8 April 2019

Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

8 April 2019

ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

8 April 2019

Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

8 April 2019

Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac T-tubule/SR microdomain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

8 April 2019

The alpha 1 isoform of Na,K-ATPase regulates cardiac contractility and functionally interacts and co-localizes with the Na/Ca exchanger in heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

8 April 2019

Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac T-tubule/SR microdomain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

postsynaptic membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

integral component of postsynaptic membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

response to muscle stretch

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

cardiac muscle contraction

1 reference

8 April 2019

Functional adult myocardium in the absence of Na+-Ca2+ exchange: cardiac-specific knockout of NCX1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

Targeted disruption of Na+/Ca2+ exchanger gene leads to cardiomyocyte apoptosis and defects in heartbeat

IGI

calcium ion homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

sodium ion transmembrane transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

regulation of the force of heart contraction

1 reference

8 April 2019

Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

positive regulation of bone mineralization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

cellular sodium ion homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

1 reference

8 April 2019

Functional adult myocardium in the absence of Na+-Ca2+ exchange: cardiac-specific knockout of NCX1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

embryonic placenta development

IGI

1 reference

8 April 2019

A novel mutant allele of Ncx1: a single amino acid substitution leads to cardiac dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

post-embryonic development

1 reference

8 April 2019

Functional adult myocardium in the absence of Na+-Ca2+ exchange: cardiac-specific knockout of NCX1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

relaxation of smooth muscle

IGI

1 reference

8 April 2019

Targeted disruption of Na+/Ca2+ exchanger gene leads to cardiomyocyte apoptosis and defects in heartbeat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

Targeted disruption of Na+/Ca2+ exchanger gene leads to cardiomyocyte apoptosis and defects in heartbeat

regulation of heart rate

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

embryonic heart tube development

1 reference

8 April 2019

A novel mutant allele of Ncx1: a single amino acid substitution leads to cardiac dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

transmembrane transport

1 reference

8 April 2019

cellular response to caffeine

1 reference

8 April 2019

Targeted disruption of Na+/Ca2+ exchanger gene leads to cardiomyocyte apoptosis and defects in heartbeat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

regulation of cardiac muscle cell membrane potential

1 reference

8 April 2019

Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange

TAS

calcium ion transport

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

8 April 2019

Genetic manipulation of cardiac Na+/Ca2+ exchange expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

8 April 2019

A circularized sodium-calcium exchanger exon 2 transcript

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

vascular associated smooth muscle contraction

IDA

1 reference

8 April 2019

Targeted disruption of Na+/Ca2+ exchanger gene leads to cardiomyocyte apoptosis and defects in heartbeat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

negative regulation of cytosolic calcium ion concentration

1 reference

8 April 2019

Targeted disruption of Na+/Ca2+ exchanger gene leads to cardiomyocyte apoptosis and defects in heartbeat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

positive regulation of the force of heart contraction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

cellular response to reactive oxygen species

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

regulation of sodium ion transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

8 April 2019

Genetic manipulation of cardiac Na+/Ca2+ exchange expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

8 April 2019

A circularized sodium-calcium exchanger exon 2 transcript

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

cellular calcium ion homeostasis

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

positive regulation of cytosolic calcium ion concentration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

positive regulation of fibroblast migration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

regulation of calcium ion transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

regulation of postsynaptic membrane potential

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

cellular response to cAMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

cell communication by electrical coupling involved in cardiac conduction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414

regulation of postsynaptic cytosolic calcium ion concentration

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70414