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GM2 ganglioside activator protein
mammalian protein found in Mus musculus
Gm2a
SAP-3
ganglioside GM2 activator
shingolipid activator protein 3
sphingolipid activator protein 3
cerebroside sulfate activator protein
GM2-AP
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q60648
part of
Ganglioside GM2 activator
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q60648
GM2-AP, lipid-recognition domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q60648
MD-2-related lipid-recognition domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q60648
encoded by
Gm2a
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q60648
molecular function
lipid transporter activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IEA
phospholipase activator activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IEA
beta-N-acetylgalactosaminidase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IEA
beta-N-acetylhexosaminidase activity
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
No requirement for V(D)J recombination in p53-deficient thymic lymphoma
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IMP
enzyme activator activity
determination method
IDA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IEA
retrieved
14 February 2019
stated in
GM2 activator protein expression in mouse tissues
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IDA
hydrolase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q60648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IEA
cell component
cytoplasm
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IEA
apical cortex
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60648&geneProductId=UniProtKB:Q60648
determination method
IEA
mitochondrion
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60648&geneProductId=UniProtKB:Q60648
determination method
IDA
potassium:proton exchanging ATPase complex
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60648&geneProductId=UniProtKB:Q60648
determination method
IEA
cytoplasmic side of plasma membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IEA
lysosome
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q60648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IEA
mitochondrion
determination method
HDA
1 reference
retrieved
14 February 2019
stated in
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
HDA
basolateral plasma membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IEA
apical plasma membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IEA
biological process
positive regulation of hydrolase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IEA
lipid transport
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IEA
neuromuscular process controlling balance
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Mouse model of GM2 activator deficiency manifests cerebellar pathology and motor impairment
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IMP
lipid metabolism
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q60648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IEA
lipid storage
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Mouse model of GM2 activator deficiency manifests cerebellar pathology and motor impairment
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IMP
nervous system process
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Mouse model of GM2 activator deficiency manifests cerebellar pathology and motor impairment
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IMP
learning or memory
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Mouse model of GM2 activator deficiency manifests cerebellar pathology and motor impairment
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IMP
oligosaccharide catabolic process
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
No requirement for V(D)J recombination in p53-deficient thymic lymphoma
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IMP
ganglioside metabolic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IEA
ganglioside catabolic process
determination method
IEA
IMP
2 references
retrieved
14 February 2019
stated in
Mouse model of GM2 activator deficiency manifests cerebellar pathology and motor impairment
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IMP
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IEA
sphingolipid metabolic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q60648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60648
determination method
IEA
has part(s)
MD-2-related lipid-recognition domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q60648
Identifiers
RefSeq protein ID
NP_034429
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
14667
UniProt protein ID
Q60648
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q60648
Ensembl protein ID
ENSMUSP00000000608
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000000608
PDB structure ID
2AGC
1 reference
stated in
UniProt
UniProt protein ID
Q60648
retrieved
21 March 2016
language of work or name
English
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