(Q21988595)

http://www.ebi.ac.uk/interpro/protein/Q8CI59

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Ferric reductase transmembrane component-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Pyrroline-5-carboxylate reductase, catalytic, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

cupric reductase activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CI59&geneProductId=UniProtKB:Q8CI59

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

IDA

oxidoreductase activity

1 reference

14 February 2019

ferric-chelate reductase activity

1 reference

14 February 2019

A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

identical protein binding

IPI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

ferric-chelate reductase (NADPH) activity

ISO

3 references

14 February 2019

Identification of a Steap3 endosomal targeting motif essential for normal iron metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

integral component of membrane

IBA

cell component

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

integral component of plasma membrane

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CI59&geneProductId=UniProtKB:Q8CI59

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

1 reference

14 February 2019

TSAP6 facilitates the secretion of translationally controlled tumor protein/histamine-releasing factor via a nonclassical pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

14 February 2019

Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

3 references

14 February 2019

Identification of a Steap3 endosomal targeting motif essential for normal iron metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

14 February 2019

Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

1 reference

14 February 2019

Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

1 reference

14 February 2019

Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

1 reference

14 February 2019

Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

positive regulation of apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

3 references

14 February 2019

Identification of a Steap3 endosomal targeting motif essential for normal iron metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

iron ion import across cell outer membrane

IBA

3 references

14 February 2019

Identification of a Steap3 endosomal targeting motif essential for normal iron metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI59

Ferric reductase transmembrane component-like domain

IBA

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8CI59

Pyrroline-5-carboxylate reductase, catalytic, N-terminal

1 reference

stated in

InterPro Release 71.0