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(Q21988997)
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RIC8 guanine nucleotide exchange factor A
mammalian protein found in Mus musculus
Protein Ric-8A
resistance to inhibitors of cholinesterase 8 homolog
synembryn
synembryn-A
Ric8a
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q3TIR3
part of
Armadillo-like helical
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q3TIR3
Guanine nucleotide exchange factor, Ric8
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q3TIR3
Armadillo-type fold
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q3TIR3
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
Synembryn domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q3TIR3
encoded by
Ric8a
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q3TIR3
molecular function
protein binding
determination method
IPI
1 reference
retrieved
14 February 2019
stated in
Regulation of type V adenylate cyclase by Ric8a, a guanine nucleotide exchange factor
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IPI
GTPase activator activity
determination method
IBA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
ISO
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IBA
guanyl-nucleotide exchange factor activity
determination method
IBA
IEA
ISO
3 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q3TIR3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IBA
G-protein alpha-subunit binding
determination method
ISO
IBA
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
ISO
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IBA
cell component
cytosol
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
ISO
plasma membrane
determination method
IBA
ISS
IEA
ISO
4 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q3TIR3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q3TIR3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IBA
membrane
determination method
IDA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q3TIR3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IEA
retrieved
14 February 2019
stated in
Regulation of type V adenylate cyclase by Ric8a, a guanine nucleotide exchange factor
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IDA
cytoplasm
determination method
IBA
IEA
ISO
ISS
4 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q3TIR3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q3TIR3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IBA
biological process
in utero embryonic development
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Heterozygous mice with Ric-8 mutation exhibit impaired spatial memory and decreased anxiety
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IMP
vasculature development
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Nucleotide exchange factor RIC-8 is indispensable in mammalian early development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IMP
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Regulation of type V adenylate cyclase by Ric8a, a guanine nucleotide exchange factor
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IDA
response to light stimulus
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Heterozygous mice with Ric-8 mutation exhibit impaired spatial memory and decreased anxiety
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IMP
basement membrane organization
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Nucleotide exchange factor RIC-8 is indispensable in mammalian early development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IMP
gastrulation
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Nucleotide exchange factor RIC-8 is indispensable in mammalian early development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IMP
visual learning
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Heterozygous mice with Ric-8 mutation exhibit impaired spatial memory and decreased anxiety
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IMP
cell-cell adhesion involved in gastrulation
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Nucleotide exchange factor RIC-8 is indispensable in mammalian early development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IMP
regulation of G protein-coupled receptor signaling pathway
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
ISO
cell migration involved in gastrulation
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Nucleotide exchange factor RIC-8 is indispensable in mammalian early development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IMP
positive regulation of GTPase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IEA
G protein-coupled receptor signaling pathway
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TIR3
determination method
IBA
has part(s)
Synembryn domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q3TIR3
Identifiers
RefSeq protein ID
NP_444424
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
101489
UniProt protein ID
Q3TIR3
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q3TIR3
Ensembl protein ID
ENSMUSP00000026558
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000026558
ENSMUSP00000147773
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000147773
ENSMUSP00000147952
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000147952
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