(Q21989882)

EF-hand domain pair

1 reference

Voltage-dependent channel domain superfamily

1 reference

EF-hand domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Polycystin cation channel, PKD1/PKD2, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

14 February 2019

Identification of the structural motif responsible for trimeric assembly of the C-terminal regulatory domains of polycystin channels PKD2L1 and PKD2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

calcium channel activity

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2A259&geneProductId=UniProtKB:A2A259

16 July 2018

Primary cilia are specialized calcium signalling organelles

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2A259&geneProductId=UniProtKB:A2A259

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2A259&geneProductId=UniProtKB:A2A259

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2A259&geneProductId=UniProtKB:A2A259

cation transmembrane transporter activity

1 reference

9 May 2019

Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

3 references

9 May 2019

Genomic organization and functional analysis of murine PKD2L1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

IPI

cation channel activity

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

Genomic organization and functional analysis of murine PKD2L1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

The asparagine 533 residue in the outer pore loop region of the mouse PKD2L1 channel is essential for its voltage-dependent inactivation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

identical protein binding

sour taste receptor activity

IPI

1 reference

9 May 2019

Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

calcium channel activity

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

Primary cilia are specialized calcium signalling organelles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

sodium channel activity

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

Identification of the structural motif responsible for trimeric assembly of the C-terminal regulatory domains of polycystin channels PKD2L1 and PKD2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

calcium-activated potassium channel activity

muscle alpha-actinin binding

integral component of membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

calcium channel complex

3 references

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2A259&geneProductId=UniProtKB:A2A259

11 October 2018

Primary cilia are specialized calcium signalling organelles

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2A259&geneProductId=UniProtKB:A2A259

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2A259&geneProductId=UniProtKB:A2A259

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2A259&geneProductId=UniProtKB:A2A259

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2A259&geneProductId=UniProtKB:A2A259

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2A259&geneProductId=UniProtKB:A2A259

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2A259&geneProductId=UniProtKB:A2A259

1 reference

9 May 2019

Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

Genomic organization and functional analysis of murine PKD2L1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

1 reference

9 May 2019

Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor

cation channel complex

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

integral component of plasma membrane

calcium channel complex

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

Primary cilia are specialized calcium signalling organelles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

Cryo-EM structure of the polycystic kidney disease-like channel PKD2L1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

Genomic organization and functional analysis of murine PKD2L1

endoplasmic reticulum

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

1 reference

9 May 2019

Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

protein homotrimerization

calcium ion transmembrane transport

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

detection of mechanical stimulus

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

smoothened signaling pathway

1 reference

9 May 2019

Primary cilia are specialized calcium signalling organelles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

detection of chemical stimulus involved in sensory perception of sour taste

IMP

1 reference

9 May 2019

Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

calcium ion transport

1 reference

9 May 2019

protein homotetramerization

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2A259&geneProductId=UniProtKB:A2A259

protein homotrimerization

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2A259&geneProductId=UniProtKB:A2A259

inorganic cation transmembrane transport

ISO

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=A2A259&geneProductId=UniProtKB:A2A259

1 reference

9 May 2019

The cellular mechanism for water detection in the mammalian taste system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

detection of chemical stimulus involved in sensory perception of taste

IMP

1 reference

9 May 2019

The cellular mechanism for water detection in the mammalian taste system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

Cryo-EM structure of the polycystic kidney disease-like channel PKD2L1.

IMP

protein tetramerization

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

The asparagine 533 residue in the outer pore loop region of the mouse PKD2L1 channel is essential for its voltage-dependent inactivation

cellular response to pH

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

inorganic cation transmembrane transport

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

9 May 2019

The asparagine 533 residue in the outer pore loop region of the mouse PKD2L1 channel is essential for its voltage-dependent inactivation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A2A259

potassium ion transmembrane transport

polycystin cation channel, PKD1/PKD2

1 reference

EF-hand domain

1 reference