(Q21990307)

Immunoglobulin-like fold

1 reference

Protein kinase-like domain superfamily

1 reference

Immunoglobulin-like domain superfamily

1 reference

membrane proteins

1 reference

inferred from GOA cell component → membrane

Immunoglobulin I-set, protein family

1 reference

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

Immunoglobulin subtype, protein family

1 reference

Immunoglobulin subtype 2, protein family

1 reference

Protein kinase domain, protein family

1 reference

immunoglobulin-like domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Tyrosine-protein kinase, catalytic domain, protein family

1 reference

Tyrosine-protein kinase, receptor class III, conserved site, protein family

1 reference

Tyrosine-protein kinase, active site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

protein kinase activity

1 reference

14 February 2019

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

growth factor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

identical protein binding

1 reference

14 February 2019

Protein-protein interaction panel using mouse full-length cDNAs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

placental growth factor-activated receptor activity

IPI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

protein tyrosine kinase activity

vascular endothelial growth factor-activated receptor activity

2 references

3 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

7 November 2018

Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

protein homodimerization activity

IDA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

ISS

receptor tyrosine kinase

3 references

10 September 2018

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

transmembrane signaling receptor activity

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

transmembrane receptor protein tyrosine kinase activity

vascular endothelial growth factor-activated receptor activity

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

14 February 2019

Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

1 reference

14 February 2019

The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

vascular endothelial growth factor binding

IPI

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

1 reference

27 March 2018

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

1 reference

14 February 2019

Intracellular VEGF regulates the balance between osteoblast and adipocyte differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

integral component of membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

integral component of plasma membrane

1 reference

14 February 2019

Role of the vasohibin family in the regulation of fetoplacental vascularization and syncytiotrophoblast formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

integral component of plasma membrane

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

post-embryonic camera-type eye morphogenesis

biological process

1 reference

14 February 2019

Flt1 and Flk1 mediate regulation of intraocular pressure and their double heterozygosity causes the buphthalmia in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

positive regulation of phosphatidylinositol 3-kinase signaling

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

vascular endothelial growth factor receptor-1 signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

embryonic morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

Local guidance of emerging vessel sprouts requires soluble Flt-1

sprouting angiogenesis

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

multicellular organism development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

1 reference

14 February 2019

Soluble Flt-1 regulates Flk-1 activation to control hematopoietic and endothelial development in an oxygen-responsive manner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

positive regulation of phospholipase C activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

branching involved in blood vessel morphogenesis

1 reference

14 February 2019

The VEGF receptor flt-1 (VEGFR-1) is a positive modulator of vascular sprout formation and branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

blood vessel morphogenesis

1 reference

14 February 2019

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

positive regulation of phosphatidylinositol 3-kinase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

protein phosphorylation

1 reference

14 February 2019

positive regulation of cell migration

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

positive regulation of vascular endothelial growth factor receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

transmembrane receptor protein tyrosine kinase signaling pathway

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

positive regulation of MAPK cascade

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

positive regulation of MAP kinase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

cellular response to vascular endothelial growth factor stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

positive regulation of hematopoietic progenitor cell differentiation

1 reference

14 February 2019

Soluble Flt-1 regulates Flk-1 activation to control hematopoietic and endothelial development in an oxygen-responsive manner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

positive regulation of angiogenesis

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

peptidyl-tyrosine phosphorylation

2 references

3 references

14 February 2019

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

14 February 2019

The VEGF receptor flt-1 (VEGFR-1) is a positive modulator of vascular sprout formation and branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

vascular endothelial growth factor receptor signaling pathway

4 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

7 November 2018

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

7 November 2018

Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

3 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

7 November 2018

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

7 November 2018

Vascular endothelial growth factor A (VEGF-A) is involved in guidance of VEGF receptor-positive cells to the anterior portion of early embryos

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

protein autophosphorylation

IGI

ISS

vascular endothelial growth factor signaling pathway

2 references

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

negative regulation of vascular endothelial cell proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

negative regulation of signal transduction

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

negative regulation of apoptotic process

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35969&geneProductId=UniProtKB:P35969

positive regulation of ERK1 and ERK2 cascade

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

positive regulation of cell population proliferation

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

14 February 2019

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

14 February 2019

Vascular endothelial growth factor A (VEGF-A) is involved in guidance of VEGF receptor-positive cells to the anterior portion of early embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

vascular endothelial growth factor receptor signaling pathway

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

14 February 2019

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

14 February 2019

Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35969

has part(s)

immunoglobulin subtype

1 reference

tyrosine-protein kinase, receptor class III, conserved site

1 reference

immunoglobulin subtype 2

1 reference

tyrosine-protein kinase, catalytic domain

1 reference

tyrosine-protein kinase, active site

1 reference

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

immunoglobulin-like domain

1 reference

protein kinase, ATP binding site

1 reference

immunoglobulin I-set

1 reference

protein kinase domain

1 reference