(Q21990371)

English

Notch 4

mammalian protein found in Mus musculus

Notch gene homolog 4
neurogenic locus notch homolog protein 4
Notch4

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

neurogenic locus Notch 4

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31695

Notch-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31695

Growth factor receptor cysteine-rich domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31695

Ankyrin repeat-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31695

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Notch, NODP domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

based on heuristic

inferred from protein domain or family

Notch, NOD domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ankyrin repeat-containing domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like calcium-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like calcium-binding, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ankyrin repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

calcium ion binding

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

determination method

1 reference

14 February 2019

Notch4 reveals a novel mechanism regulating Notch signal transduction

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

protein binding

determination method

3 references

9 May 2019

RBP-L, a transcription factor related to RBP-Jkappa

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

9 May 2019

Impaired angiogenesis and altered Notch signaling in mice overexpressing endothelial Egfl7

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

9 May 2019

sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

signaling receptor activity

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

plasma membrane

determination method

1 reference

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31695&geneProductId=UniProtKB:P31695

determination method

endoplasmic reticulum

determination method

1 reference

9 May 2019

Notch4 reveals a novel mechanism regulating Notch signal transduction

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

cytoplasmic vesicle

determination method

1 reference

9 May 2019

Notch4 reveals a novel mechanism regulating Notch signal transduction

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

plasma membrane

determination method

2 references

plasma membrane

determination method

biological process

Notch signaling pathway

determination method

3 references

9 May 2019

Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

positive regulation of aorta morphogenesis

determination method

1 reference

9 May 2019

Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

regulation of transcription, DNA-templated

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

venous blood vessel morphogenesis

determination method

1 reference

9 May 2019

Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

negative regulation of endothelial cell differentiation

determination method

1 reference

9 May 2019

Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

morphogenesis of a branching structure

determination method

1 reference

9 May 2019

Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

transcription, DNA-templated

determination method

1 reference

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31695&geneProductId=UniProtKB:P31695

determination method

positive regulation of angiogenesis

determination method

1 reference

9 May 2019

Notch4 reveals a novel mechanism regulating Notch signal transduction

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

regulation of protein processing

determination method

1 reference

9 May 2019

Notch4 reveals a novel mechanism regulating Notch signal transduction

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

mammary gland development

determination method

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

regulation of protein localization

determination method

1 reference

9 May 2019

Notch4 reveals a novel mechanism regulating Notch signal transduction

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

branching involved in blood vessel morphogenesis

determination method

1 reference

9 May 2019

Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

regulation of Notch signaling pathway

determination method

1 reference

9 May 2019

Notch4 reveals a novel mechanism regulating Notch signal transduction

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

negative regulation of Notch signaling pathway

determination method

1 reference

14 February 2019

Notch4 reveals a novel mechanism regulating Notch signal transduction

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

regulation of developmental process

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

vasculature development

determination method

1 reference

9 May 2019

Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

endothelial cell morphogenesis

determination method

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

endothelial cell differentiation

determination method

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31695

determination method

ankyrin repeat-containing domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31695

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31695

EGF-like calcium-binding, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31695

EGF-like calcium-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31695

EGF-like, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31695

Notch, NOD domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31695

EGF-type aspartate/asparagine hydroxylation site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31695

Notch, NODP domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31695

EGF-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31695

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31695

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000015612

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000015612

ENSMUSP00000133574

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000133574

ENSMUSP00000133646

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000133646

ENSMUSP00000134497

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000134497

Sitelinks

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Wikisource(0 entries)

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Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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