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(Q21990605)
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Selection and upkeep of intraepithelial T cells 1
mammalian protein found in Mus musculus
Skint1
Immunoglobulin-like and transmembrane domain-containing protein expressed in skin and thymus protein 1
selection and upkeep of intraepithelial T-cells protein 1
skint 1
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
A7TZE6
part of
Immunoglobulin-like fold
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/A7TZE6
Immunoglobulin-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/A7TZE6
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
Immunoglobulin subtype, protein family
1 reference
based on heuristic
inferred from protein domain or family
Immunoglobulin V-set domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
immunoglobulin-like domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
A7TZE6
encoded by
Skint1
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
A7TZE6
molecular function
molecular function
determination method
ND
1 reference
retrieved
16 July 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=A7TZE6&geneProductId=UniProtKB:A7TZE6
determination method
ND
signaling receptor binding
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A7TZE6
determination method
IBA
cell component
integral component of membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
A7TZE6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A7TZE6
determination method
IEA
membrane
determination method
ISM
IEA
2 references
retrieved
14 February 2019
stated in
Skint1, the prototype of a newly identified immunoglobulin superfamily gene cluster, positively selects epidermal gammadelta T cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A7TZE6
determination method
ISM
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
A7TZE6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A7TZE6
determination method
IEA
cell periphery
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Skint-1 is a highly specific, unique selecting component for epidermal T cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A7TZE6
determination method
IDA
external side of plasma membrane
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A7TZE6
determination method
IBA
biological process
positive regulation of T cell differentiation
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Skint-1 is a highly specific, unique selecting component for epidermal T cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A7TZE6
determination method
IDA
positive regulation of T cell differentiation in thymus
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Skint-1 identifies a common molecular mechanism for the development of interferon-γ-secreting versus interleukin-17-secreting γδ T cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A7TZE6
determination method
IMP
positive thymic T cell selection
determination method
IDA
IMP
2 references
retrieved
14 February 2019
stated in
Skint1, the prototype of a newly identified immunoglobulin superfamily gene cluster, positively selects epidermal gammadelta T cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A7TZE6
determination method
IMP
retrieved
14 February 2019
stated in
Skint-1 is a highly specific, unique selecting component for epidermal T cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A7TZE6
determination method
IDA
regulation of immune response
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A7TZE6
determination method
IBA
T cell receptor signaling pathway
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A7TZE6
determination method
IBA
has part(s)
immunoglobulin subtype
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/A7TZE6
immunoglobulin V-set domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/A7TZE6
immunoglobulin-like domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/A7TZE6
Identifiers
RefSeq protein ID
NP_001096132
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
639781
UniProt protein ID
A7TZE6
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
A7TZE6
Ensembl protein ID
ENSMUSP00000125625
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000125625
ENSMUSP00000124545
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000124545
ENSMUSP00000125313
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000125313
ENSMUSP00000124737
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000124737
PDB structure ID
2N4I
1 reference
stated in
UniProt
UniProt protein ID
A7TZE6
retrieved
20 March 2016
language of work or name
English
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