(Q21990719)

English

Tropomodulin 1

mammalian protein found in Mus musculus

E-Tmod
erythrocyte tropomodulin
tropomodulin-1
Tmod1

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49813

Leucine-rich repeat domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P49813

membrane proteins

1 reference

based on heuristic

inferred from GOA cell component → membrane

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

actin filament binding

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

determination method

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

tropomyosin binding

determination method

3 references

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49813&geneProductId=UniProtKB:P49813

determination method

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49813&geneProductId=UniProtKB:P49813

determination method

24 April 2018

Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49813&geneProductId=UniProtKB:P49813

determination method

tropomyosin binding

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

14 February 2019

Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

COP9 signalosome

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

cortical cytoskeleton

determination method

1 reference

14 February 2019

Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

determination method

1 reference

14 February 2019

Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

determination method

3 references

determination method

4 references

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49813&geneProductId=UniProtKB:P49813

determination method

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49813&geneProductId=UniProtKB:P49813

determination method

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49813&geneProductId=UniProtKB:P49813

determination method

24 April 2018

Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49813&geneProductId=UniProtKB:P49813

determination method

determination method

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

14 February 2019

A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

striated muscle thin filament

determination method

3 references

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

determination method

2 references

determination method

5 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

14 February 2019

Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

biological process

adult locomotory behavior

determination method

1 reference

14 February 2019

Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

pointed-end actin filament capping

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

muscle contraction

determination method

1 reference

24 April 2018

Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49813&geneProductId=UniProtKB:P49813

determination method

myofibril assembly

determination method

1 reference

24 April 2018

Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49813&geneProductId=UniProtKB:P49813

determination method

lens fiber cell development

determination method

1 reference

14 February 2019

Tmod1 and CP49 synergize to control the fiber cell geometry, transparency, and mechanical stiffness of the mouse lens

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49813

determination method

actin filament organization

determination method

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49813&geneProductId=UniProtKB:P49813

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000103402

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000103402

ENSMUSP00000134075

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000134075

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