(Q21990751)

Immunoglobulin-like fold

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Fibronectin type III, protein family

1 reference

inferred from protein domain or family

Growth hormone/erythropoietin receptor, ligand binding domain, protein family

1 reference

inferred from protein domain or family

Long hematopoietin receptor, single chain, conserved site, protein family

1 reference

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

cytokine receptor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

thrombopoietin receptor activity

IEA

2 references

integral component of membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

3 references

3 references

2 references

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

regulation of chemokine production

biological process

1 reference

14 February 2019

CXCL5 regulates chemokine scavenging and pulmonary host defense to bacterial infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

Mpl receptor defect leads to earlier appearance of hematopoietic cells/hematopoietic stem cells in the Aorta-Gonad-Mesonephros region, with increased apoptosis

definitive hemopoiesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

positive regulation of gene expression

1 reference

14 February 2019

Mpl receptor defect leads to earlier appearance of hematopoietic cells/hematopoietic stem cells in the Aorta-Gonad-Mesonephros region, with increased apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

1 reference

14 February 2019

Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl-/- mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

negative regulation of apoptotic process

IGI

1 reference

14 February 2019

Mpl receptor defect leads to earlier appearance of hematopoietic cells/hematopoietic stem cells in the Aorta-Gonad-Mesonephros region, with increased apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

regulation of stem cell division

1 reference

14 February 2019

Mpl receptor defect leads to earlier appearance of hematopoietic cells/hematopoietic stem cells in the Aorta-Gonad-Mesonephros region, with increased apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

regulation of stem cell proliferation

1 reference

14 February 2019

Mpl receptor defect leads to earlier appearance of hematopoietic cells/hematopoietic stem cells in the Aorta-Gonad-Mesonephros region, with increased apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

homeostasis of number of cells

1 reference

14 February 2019

CXCL5 regulates chemokine scavenging and pulmonary host defense to bacterial infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

thrombopoietin-mediated signaling pathway

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08351&geneProductId=UniProtKB:Q08351

cytokine-mediated signaling pathway

IEA

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08351&geneProductId=UniProtKB:Q08351

IEA

neutrophil homeostasis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

positive regulation of lymphocyte proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

positive regulation of platelet formation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

eosinophil homeostasis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

thrombopoietin-mediated signaling pathway

1 reference

14 February 2019

Ott1 (Rbm15) regulates thrombopoietin response in hematopoietic stem cells through alternative splicing of c-Mpl

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08351

Long hematopoietin receptor, single chain, conserved site

IDA

has part(s)

1 reference

fibronectin type III

1 reference

Growth hormone/erythropoietin receptor, ligand binding

1 reference