(Q21991517)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8BGV3

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Thyroglobulin type-1, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BGV3&geneProductId=UniProtKB:Q8BGV3

cadherin binding involved in cell-cell adhesion

ND

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGV3

integral component of membrane

cell component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGV3

1 reference

14 February 2019

IEA

plasma membrane

1 reference

14 February 2019

Cloning of the murine TROP2 gene: conservation of a PIP2-binding sequence in the cytoplasmic domain of TROP-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGV3

basal plasma membrane

1 reference

14 February 2019

TROP2 expressed in the trunk of the ureteric duct regulates branching morphogenesis during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGV3

lateral plasma membrane

1 reference

14 February 2019

TROP2 expressed in the trunk of the ureteric duct regulates branching morphogenesis during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGV3

nucleus

1 reference

31 January 2018

Regulated proteolysis of Trop2 drives epithelial hyperplasia and stem cell self-renewal via β-catenin signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BGV3&geneProductId=UniProtKB:Q8BGV3

integral component of plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BGV3&geneProductId=UniProtKB:Q8BGV3

1 reference

31 January 2018

extracellular space

1 reference

31 January 2018

Regulated proteolysis of Trop2 drives epithelial hyperplasia and stem cell self-renewal via β-catenin signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BGV3&geneProductId=UniProtKB:Q8BGV3

bicellular tight junction

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGV3

ureteric bud morphogenesis

biological process

1 reference

14 February 2019

TROP2 expressed in the trunk of the ureteric duct regulates branching morphogenesis during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGV3

negative regulation of branching involved in ureteric bud morphogenesis

1 reference

14 February 2019

TROP2 expressed in the trunk of the ureteric duct regulates branching morphogenesis during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGV3

negative regulation of cell motility

1 reference

14 February 2019

TROP2 expressed in the trunk of the ureteric duct regulates branching morphogenesis during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGV3

negative regulation of stress fiber assembly

1 reference

14 February 2019

TROP2 expressed in the trunk of the ureteric duct regulates branching morphogenesis during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGV3

negative regulation of substrate adhesion-dependent cell spreading

1 reference

14 February 2019

TROP2 expressed in the trunk of the ureteric duct regulates branching morphogenesis during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGV3

positive regulation of stem cell differentiation

1 reference

31 January 2018

Regulated proteolysis of Trop2 drives epithelial hyperplasia and stem cell self-renewal via β-catenin signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BGV3&geneProductId=UniProtKB:Q8BGV3

regulation of epithelial cell proliferation

1 reference

14 February 2019

TROP2 expressed in the trunk of the ureteric duct regulates branching morphogenesis during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGV3

negative regulation of epithelial cell migration

1 reference

14 February 2019

TROP2 expressed in the trunk of the ureteric duct regulates branching morphogenesis during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGV3

negative regulation of ruffle assembly

1 reference

14 February 2019

TROP2 expressed in the trunk of the ureteric duct regulates branching morphogenesis during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGV3

cell-cell adhesion

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BGV3&geneProductId=UniProtKB:Q8BGV3

1 reference

31 January 2018

cell-cell adhesion

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGV3

positive regulation of stem cell differentiation

IEA

1 reference

InterPro Release 71.0