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(Q21991769)
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Synemin, intermediate filament protein
mammalian protein found in Mus musculus
Synm
Desmuslin
synemin
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q70IV5
part of
Synemin
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q70IV5
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
Intermediate filament, rod domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Intermediate filament protein, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q70IV5
encoded by
Synm
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q70IV5
molecular function
vinculin binding
determination method
ISS
IEA
ISO
3 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q70IV5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IEA
protein-macromolecule adaptor activity
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
ISO
structural constituent of muscle
determination method
ISS
IEA
ISO
4 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q70IV5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IEA
structural constituent of cytoskeleton
determination method
ISS
IEA
ISO
4 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q70IV5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IEA
protein binding
determination method
IPI
2 references
retrieved
14 February 2019
stated in
Synemin is expressed in reactive astrocytes in neurotrauma and interacts differentially with vimentin and GFAP intermediate filament networks
GOA
curator
UniProt
UniProt protein ID
Q70IV5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IPI
retrieved
14 February 2019
stated in
α-Synemin localizes to the M-band of the sarcomere through interaction with the M10 region of titin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IPI
intermediate filament binding
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
The mouse synemin gene encodes three intermediate filament proteins generated by alternative exon usage and different open reading frames
GOA
curator
UniProt
UniProt protein ID
Q70IV5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IDA
structural molecule activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IEA
cell component
cytoplasm
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q70IV5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IEA
adherens junction
determination method
ISS
IEA
ISO
4 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q70IV5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q70IV5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IEA
cell junction
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q70IV5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IEA
neurofilament cytoskeleton
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Different expression of synemin isoforms in glia and neurons during nervous system development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IDA
sarcolemma
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Myopathic changes in murine skeletal muscle lacking synemin
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IDA
costamere
determination method
ISS
IEA
ISO
3 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q70IV5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IEA
Z disc
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
ISO
cytoskeleton
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q70IV5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IEA
intermediate filament
determination method
ISS
IEA
ISO
5 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q70IV5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q70IV5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IEA
membrane
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Different expression of synemin isoforms in glia and neurons during nervous system development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IDA
biological process
fast-twitch skeletal muscle fiber contraction
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Myopathic changes in murine skeletal muscle lacking synemin
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IMP
intermediate filament cytoskeleton organization
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q70IV5
determination method
IEA
has part(s)
Intermediate filament protein, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q70IV5
Intermediate filament, rod domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q70IV5
Identifiers
RefSeq protein ID
NP_899135
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
233335
NP_964001
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
233335
NP_997546
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
233335
UniProt protein ID
Q70IV5
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q70IV5
Ensembl protein ID
ENSMUSP00000050987
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000050987
ENSMUSP00000073855
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000073855
ENSMUSP00000146510
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000146510
ENSMUSP00000147089
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000147089
ENSMUSP00000147111
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000147111
Sitelinks
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Multilingual sites
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