(Q21992274)

English

Unc-13 homolog B

mammalian protein found in Mus musculus

Unc13b
protein unc-13 homolog B
unc13 homolog 1
Munc13-2
unc-13 homolog A
munc13
UNC-13 homolog 1

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

C2 domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Z1N9

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Z1N9

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Calcium-dependent secretion activator domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Munc13 homology 1, protein family

1 reference

based on heuristic

inferred from protein domain or family

C2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein Unc-13, C2B domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Mammalian uncoordinated homology 13, domain 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

metal ion binding

determination method

2 references

UniProt protein ID

9 August 2016

language of work or name

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

diacylglycerol binding

determination method

2 references

UniProt protein ID

9 August 2016

language of work or name

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

calcium ion binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

phospholipid binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

syntaxin binding

determination method

1 reference

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

Golgi apparatus

determination method

neuromuscular junction

determination method

1 reference

16 September 2017

Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1N9&geneProductId=UniProtKB:Q9Z1N9

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

plasma membrane

determination method

1 reference

16 September 2017

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1N9&geneProductId=UniProtKB:Q9Z1N9

determination method

early phagosome

determination method

1 reference

8 April 2019

Size-dependent mechanism of cargo sorting during lysosome-phagosome fusion is controlled by Rab34

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

determination method

3 references

8 April 2019

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

8 April 2019

The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

8 April 2019

The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

presynaptic active zone

determination method

determination method

1 reference

8 April 2019

Munc13-independent vesicle priming at mouse photoreceptor ribbon synapses

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

plasma membrane

determination method

3 references

synaptic vesicle membrane

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

presynaptic membrane

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

terminal bouton

determination method

3 references

presynaptic active zone

determination method

3 references

8 April 2019

Munc13-independent vesicle priming at mouse photoreceptor ribbon synapses

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

8 April 2019

Differential control of vesicle priming and short-term plasticity by Munc13 isoforms

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

synaptic membrane

determination method

1 reference

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

presynaptic active zone cytoplasmic component

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

biological process

intracellular signal transduction

determination method

2 references

UniProt protein ID

9 August 2016

language of work or name

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

synaptic vesicle docking

determination method

1 reference

UniProt protein ID

9 August 2016

language of work or name

synaptic transmission, glutamatergic

determination method

1 reference

UniProt protein ID

9 August 2016

language of work or name

regulation of short-term neuronal synaptic plasticity

determination method

3 references

neuromuscular junction development

determination method

1 reference

UniProt protein ID

9 August 2016

language of work or name

synaptic vesicle priming

determination method

1 reference

UniProt protein ID

9 August 2016

language of work or name

determination method

2 references

UniProt protein ID

9 August 2016

language of work or name

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

chemical synaptic transmission

determination method

positive regulation of inhibitory postsynaptic potential

determination method

1 reference

UniProt protein ID

9 August 2016

language of work or name

positive regulation of synaptic vesicle priming

determination method

1 reference

UniProt protein ID

9 August 2016

language of work or name

synaptic vesicle priming

determination method

5 references

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

8 April 2019

Differential control of vesicle priming and short-term plasticity by Munc13 isoforms

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

8 April 2019

Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

8 April 2019

The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

synaptic vesicle maturation

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

negative regulation of synaptic plasticity

determination method

1 reference

8 April 2019

The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

synaptic transmission, glutamatergic

determination method

3 references

8 April 2019

Differential control of vesicle priming and short-term plasticity by Munc13 isoforms

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

8 April 2019

Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

positive regulation of exocytosis

determination method

1 reference

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

spontaneous neurotransmitter secretion

determination method

1 reference

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

dense core granule docking

determination method

1 reference

8 April 2019

Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

phagosome maturation

determination method

1 reference

8 April 2019

Size-dependent mechanism of cargo sorting during lysosome-phagosome fusion is controlled by Rab34

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

positive regulation of defense response to bacterium

determination method

1 reference

8 April 2019

Size-dependent mechanism of cargo sorting during lysosome-phagosome fusion is controlled by Rab34

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

acrosomal vesicle exocytosis

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1N9

determination method

Mammalian uncoordinated homology 13, domain 2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Z1N9

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Z1N9

protein kinase C-like, phorbol ester/diacylglycerol-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Z1N9

Munc13 homology 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Z1N9

Calcium-dependent secretion activator domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Z1N9

Protein Unc-13, C2B domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Z1N9

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000078894

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000078894

ENSMUSP00000103586

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000103586

ENSMUSP00000128608

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000128608

ENSMUSP00000103587

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000103587

ENSMUSP00000128638

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000128638

ENSMUSP00000132622

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000132622

ENSMUSP00000146589

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000146589

ENSMUSP00000147100

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000147100

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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