(Q21992441)

Cystine-knot cytokine

1 reference

Transforming growth factor-beta, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

TGF-beta, propeptide family

1 reference

based on heuristic

inferred from protein domain or family

Transforming growth factor beta, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

10 August 2016

language of work or name

1 reference

10 August 2016

language of work or name

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

type II transforming growth factor beta receptor binding

identical protein binding

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

transforming growth factor beta receptor binding

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17125&geneProductId=UniProtKB:P17125

growth factor activity

transforming growth factor beta binding

2 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

protein heterodimerization activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

1 reference

14 February 2019

Glycoprotein A repetitions predominant (GARP) positively regulates transforming growth factor (TGF) β3 and is essential for mouse palatogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17125&geneProductId=UniProtKB:P17125

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

intracellular membrane-bounded organelle

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

1 reference

14 February 2019

Submandibular gland morphogenesis: stage-specific expression of TGF-alpha/EGF, IGF, TGF-beta, TNF, and IL-6 signal transduction in normal embryonic mice and the phenotypic effects of TGF-beta2, TGF-beta3, and EGF-r null mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

collagen-containing extracellular matrix

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

negative regulation of neuron apoptotic process

biological process

1 reference

14 February 2019

Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

cell-cell junction organization

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

regulation of MAPK cascade

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

SMAD protein signal transduction

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

positive regulation of bone mineralization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

ISS

response to progesterone

2 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

cellular response to growth factor stimulus

1 reference

14 February 2019

Comparative analysis of TGF beta s, BMPs, IGF1, msxs, fibronectin, osteonectin and bone sialoprotein gene expression during normal and in vitro-induced odontoblast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

positive regulation of pathway-restricted SMAD protein phosphorylation

1 reference

16 July 2018

TGFbeta3 signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17125&geneProductId=UniProtKB:P17125

in utero embryonic development

1 reference

14 February 2019

Tgf-beta3-induced palatal fusion is mediated by Alk-5/Smad pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

salivary gland morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

positive regulation of epithelial to mesenchymal transition

ISS

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

14 February 2019

TGFbeta3 signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

mammary gland development

1 reference

14 February 2019

Regulated expression and growth inhibitory effects of transforming growth factor-beta isoforms in mouse mammary gland development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

positive regulation of transcription, DNA-templated

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

14 February 2019

TGFbeta3 signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

positive regulation of gene expression

1 reference

14 February 2019

TGF-β-induced mesenchymal transition of MS-1 endothelial cells requires Smad-dependent cooperative activation of Rho signals and MRTF-A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

positive regulation of protein secretion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

ossification involved in bone remodeling

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

animal organ morphogenesis

ISS

1 reference

14 February 2019

Snail family members and cell survival in physiological and pathological cleft palates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

lung alveolus development

1 reference

14 February 2019

Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

transforming growth factor beta receptor signaling pathway

positive regulation of filopodium assembly

1 reference

14 February 2019

Epithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

positive regulation of cell division

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

14 February 2019

The role of transforming growth factor-beta signalling in the patterning of the proximal processes of the murine dentary

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

positive regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

positive regulation of SMAD protein signal transduction

IGI

1 reference

14 February 2019

TGFbeta3 signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

positive regulation of tight junction disassembly

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

positive regulation of stress fiber assembly

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

1 reference

14 February 2019

Ligand-specific function of transforming growth factor beta in epithelial-mesenchymal transition in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17125&geneProductId=UniProtKB:P17125

BMP signaling pathway

1 reference

16 July 2018

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

negative regulation of vascular associated smooth muscle cell proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

regulation of signaling receptor activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

negative regulation of cell population proliferation

3 references

negative regulation of transforming growth factor beta receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

embryonic neurocranium morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

secondary palate development

5 references

14 February 2019

Transforming growth factor-beta 3 is required for secondary palate fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

14 February 2019

Glycoprotein A repetitions predominant (GARP) positively regulates transforming growth factor (TGF) β3 and is essential for mouse palatogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

14 February 2019

Pathogenesis of cleft palate in TGF-beta3 knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

14 February 2019

TGFbeta3 signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

14 February 2019

Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

positive regulation of pathway-restricted SMAD protein phosphorylation

regulation of cell population proliferation

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

regulation of apoptotic process

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17125

Transforming growth factor-beta, C-terminal

has part(s)

1 reference

Transforming growth factor beta, conserved site

1 reference

TGF-beta, propeptide

1 reference