(Q21992479)

Death-like domain superfamily

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Death domain, protein family

1 reference

Tyrosine-protein kinase ephrin type A/B receptor-like, protein family

1 reference

Tumor necrosis factor receptor 21, N-terminal domain, protein family

1 reference

Tumor necrosis factor receptor 21, death domain, protein family

1 reference

TNFR/NGFR cysteine-rich region, protein family

1 reference

tumor necrosis factor-activated receptor activity

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPU5&geneProductId=UniProtKB:Q9EPU5

integral component of membrane

cell component

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

intrinsic component of plasma membrane

1 reference

14 February 2019

Enhanced B cell expansion, survival, and humoral responses by targeting death receptor 6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

integral component of plasma membrane

3 references

1 reference

14 February 2019

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPU5&geneProductId=UniProtKB:Q9EPU5

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

regulation of apoptotic process

biological process

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPU5&geneProductId=UniProtKB:Q9EPU5

Enhanced B cell expansion, survival, and humoral responses by targeting death receptor 6

B cell apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

regulation of oligodendrocyte differentiation

1 reference

14 February 2019

Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

immune system process

1 reference

14 February 2019

oligodendrocyte apoptotic process

1 reference

27 March 2018

Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPU5&geneProductId=UniProtKB:Q9EPU5

response to lipopolysaccharide

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPU5&geneProductId=UniProtKB:Q9EPU5

negative regulation of T cell proliferation

1 reference

27 March 2018

Enhanced CD4+ T cell proliferation and Th2 cytokine production in DR6-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPU5&geneProductId=UniProtKB:Q9EPU5

Enhanced CD4+ T cell proliferation and Th2 cytokine production in DR6-deficient mice

humoral immune response

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPU5&geneProductId=UniProtKB:Q9EPU5

apoptotic signaling pathway

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPU5&geneProductId=UniProtKB:Q9EPU5

1 reference

14 February 2019

Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPU5&geneProductId=UniProtKB:Q9EPU5

inflammatory response

1 reference

27 March 2018

negative regulation of B cell proliferation

1 reference

27 March 2018

Enhanced B cell expansion, survival, and humoral responses by targeting death receptor 6

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPU5&geneProductId=UniProtKB:Q9EPU5

T cell receptor signaling pathway

1 reference

14 February 2019

Enhanced CD4+ T cell proliferation and Th2 cytokine production in DR6-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

negative regulation of myelination

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

3 references

tumor necrosis factor-mediated signaling pathway

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPU5&geneProductId=UniProtKB:Q9EPU5

Enhanced CD4+ T cell proliferation and Th2 cytokine production in DR6-deficient mice

adaptive immune response

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPU5&geneProductId=UniProtKB:Q9EPU5

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

neuron apoptotic process

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

14 February 2019

A DR6/p75(NTR) complex is responsible for β-amyloid-induced cortical neuron death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPU5

1 reference

TNFR/NGFR cysteine-rich region

1 reference

tyrosine-protein kinase ephrin type A/B receptor-like

1 reference

Tumor necrosis factor receptor 21, death domain

1 reference

Tumor necrosis factor receptor 21, N-terminal

1 reference