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(Q21992733)
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V-set domain containing T cell activation inhibitor 1
mammalian protein found in Mus musculus
B7-H4
V-set domain containing T-cell activation inhibitor 1
t cell costimulatory molecule B7x
Protein B7S1
immune costimulatory protein B7-H4
Vtcn1
B7 homolog 4
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q7TSP5
part of
Immunoglobulin-like fold
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7TSP5
Immunoglobulin-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7TSP5
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
Immunoglobulin subtype, protein family
1 reference
based on heuristic
inferred from protein domain or family
Immunoglobulin V-set domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Immunoglobulin subtype 2, protein family
1 reference
based on heuristic
inferred from protein domain or family
immunoglobulin-like domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q7TSP5
encoded by
Vtcn1
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q7TSP5
molecular function
signaling receptor binding
determination method
IDA
IGI
2 references
retrieved
5 June 2018
stated in
Cutting edge: CD28-mediated transcriptional and posttranscriptional regulation of IL-2 expression are controlled through different signaling pathways
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TSP5&geneProductId=UniProtKB:Q7TSP5
determination method
IGI
retrieved
5 June 2018
stated in
BTNL2, a butyrophilin-like molecule that functions to inhibit T cell activation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TSP5&geneProductId=UniProtKB:Q7TSP5
determination method
IDA
signaling receptor binding
determination method
IBA
IDA
IGI
3 references
retrieved
14 February 2019
stated in
Cutting edge: CD28-mediated transcriptional and posttranscriptional regulation of IL-2 expression are controlled through different signaling pathways
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IGI
retrieved
14 February 2019
stated in
BTNL2, a butyrophilin-like molecule that functions to inhibit T cell activation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IBA
cell component
anchored component of membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7TSP5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IEA
plasma membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7TSP5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7TSP5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IEA
external side of plasma membrane
determination method
IDA
IEA
ISO
3 references
retrieved
5 June 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TSP5&geneProductId=UniProtKB:Q7TSP5
determination method
ISO
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TSP5&geneProductId=UniProtKB:Q7TSP5
determination method
IEA
retrieved
5 June 2018
stated in
Expression of the novel co-stimulatory molecule B7-H4 by renal tubular epithelial cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TSP5&geneProductId=UniProtKB:Q7TSP5
determination method
IDA
external side of plasma membrane
determination method
IBA
IDA
IEA
ISO
4 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IEA
retrieved
14 February 2019
stated in
Expression of the novel co-stimulatory molecule B7-H4 by renal tubular epithelial cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IBA
biological process
adaptive immune response
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7TSP5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IEA
positive regulation of T cell proliferation
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
BTNL2, a butyrophilin-like molecule that functions to inhibit T cell activation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IMP
response to protozoan
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Generation and characterization of B7-H4/B7S1/B7x-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IMP
immune system process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q7TSP5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IEA
negative regulation of T cell proliferation
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IEA
negative regulation of apoptotic process
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IEA
negative regulation of T cell activation
determination method
IDA
IEA
ISO
3 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IEA
retrieved
14 February 2019
stated in
Cutting edge: CD28-mediated transcriptional and posttranscriptional regulation of IL-2 expression are controlled through different signaling pathways
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IDA
regulation of immune response
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IBA
T cell receptor signaling pathway
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TSP5
determination method
IBA
has part(s)
immunoglobulin subtype
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7TSP5
immunoglobulin V-set domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7TSP5
immunoglobulin subtype 2
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7TSP5
immunoglobulin-like domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q7TSP5
Identifiers
RefSeq protein ID
NP_848709
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
242122
XP_030108480
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
242122
XP_036018998
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
242122
UniProt protein ID
Q7TSP5
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q7TSP5
Ensembl protein ID
ENSMUSP00000057721
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000057721
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