(Q2386988)

English

Apelin

mammalian protein found in Homo sapiens

APJ endogenous ligand
apelin
AGTRL1 ligand
APLN

In more languages

Statements

protein precursor

1 reference

16 January 2019

UniProt protein ID

1 reference

18 December 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ULZ1

1 reference

18 December 2019

UniProt protein ID

1 reference

18 December 2019

UniProt protein ID

molecular function

G protein-coupled receptor binding

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ULZ1&geneProductId=UniProtKB:Q9ULZ1

determination method

hormone activity

determination method

3 references

8 April 2019

Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

apelin receptor binding

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

8 April 2019

Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

protein homodimerization activity

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

perinuclear region of cytoplasm

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

extracellular space

determination method

3 references

extracellular region

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

8 April 2019

Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

biological process

positive regulation of corticotropin-releasing hormone secretion

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

negative regulation of vasoconstriction

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

regulation of the force of heart contraction

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

regulation of respiratory gaseous exchange

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

positive regulation of corticotropin secretion

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

regulation of body fluid levels

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

immune response

determination method

1 reference

8 April 2019

Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

feeding behavior

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

positive regulation of cell population proliferation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

positive regulation of heat generation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

determination method

1 reference

8 April 2019

Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

positive regulation of phosphorylation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ULZ1&geneProductId=UniProtKB:Q9ULZ1

determination method

apelin receptor signaling pathway

determination method

3 references

8 April 2019

Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

8 April 2019

Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

regulation of signaling receptor activity

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

G protein-coupled receptor signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

negative regulation of gene expression

determination method

1 reference

8 April 2019

An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

negative regulation of fibroblast growth factor receptor signaling pathway

determination method

1 reference

8 April 2019

An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

positive regulation of pri-miRNA transcription by RNA polymerase II

determination method

1 reference

8 April 2019

An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

negative regulation of vascular associated smooth muscle cell proliferation

determination method

1 reference

8 April 2019

An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

positive regulation of vascular endothelial cell proliferation

determination method

1 reference

8 April 2019

An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

multicellular organism development

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULZ1

determination method

0 references

0 references

Identifiers

RefSeq protein ID

1 reference

27 December 2019

UniProt protein ID

1 reference

18 December 2019

UniProt protein ID

0 references

Ensembl protein ID

ENSP00000391800

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000391800

1 reference

Freebase Data Dumps

publication date

28 October 2013

Microsoft Academic ID

0 references

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

Semantic Scholar topic ID

0 references

Sitelinks

Wikipedia(8 entries)

arwiki ببتيد ابيلين
enwiki Apelin
eswiki Apelina
frwiki Apeline
ruwiki Апелин
shwiki Apelin
srwiki Apelin
ukwiki Апелін

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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