(Q27547571)

English

Atg7p YHR171W

fungal protein found in Saccharomyces cerevisiae S288c

YHR171W
Atg7p
ATG7

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

Ubiquitin-like modifier-activating enzyme Atg7

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P38862

ubiquitin-activating enzyme

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P38862

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

THIF-type NAD/FAD binding fold, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ubiquitin-like modifier-activating enzyme Atg7, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

ubiquitin-like modifier activating enzyme activity

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

Atg12 activating enzyme activity

determination method

1 reference

16 July 2018

Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38862&geneProductId=UniProtKB:P38862

determination method

Atg8 activating enzyme activity

determination method

1 reference

16 July 2018

A ubiquitin-like system mediates protein lipidation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38862&geneProductId=UniProtKB:P38862

determination method

protein binding

determination method

7 references

9 May 2019

Autophagic clearance of polyQ proteins mediated by ubiquitin-Atg8 adaptors of the conserved CUET protein family

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

9 May 2019

Insights into noncanonical E1 enzyme activation from the structure of autophagic E1 Atg7 with Atg8

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

9 May 2019

A ubiquitin-like system mediates protein lipidation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

9 May 2019

Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structures

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

9 May 2019

High-quality binary protein interaction map of the yeast interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

9 May 2019

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

9 May 2019

The carboxyl terminal 17 amino acids within Apg7 are essential for Apg8 lipidation, but not for Apg12 conjugation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

determination method

1 reference

9 May 2019

Apg7p/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

extrinsic component of phagophore assembly site membrane

determination method

1 reference

9 May 2019

Apg7p/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

determination method

1 reference

10 September 2018

Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38862&geneProductId=UniProtKB:P38862

determination method

phagophore assembly site

determination method

3 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

9 May 2019

Localization of autophagy-related proteins in yeast using a versatile plasmid-based resource of fluorescent protein fusions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

determination method

biological process

late nucleophagy

determination method

1 reference

16 July 2018

A late form of nucleophagy in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38862&geneProductId=UniProtKB:P38862

determination method

determination method

autophagy of mitochondrion

determination method

1 reference

16 July 2018

A genomic screen for yeast mutants defective in selective mitochondria autophagy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38862&geneProductId=UniProtKB:P38862

determination method

protein modification by small protein conjugation

determination method

1 reference

10 September 2018

Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38862&geneProductId=UniProtKB:P38862

determination method

C-terminal protein lipidation

determination method

6 references

16 July 2018

The carboxyl terminal 17 amino acids within Apg7 are essential for Apg8 lipidation, but not for Apg12 conjugation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38862&geneProductId=UniProtKB:P38862

determination method

16 July 2018

The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38862&geneProductId=UniProtKB:P38862

determination method

16 July 2018

In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38862&geneProductId=UniProtKB:P38862

determination method

16 July 2018

A ubiquitin-like system mediates protein lipidation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38862&geneProductId=UniProtKB:P38862

determination method

16 July 2018

In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38862&geneProductId=UniProtKB:P38862

determination method

16 July 2018

Mutation at the cargo-receptor binding site of Atg8 also affects its general autophagy regulation function

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38862&geneProductId=UniProtKB:P38862

determination method

protein transport

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

piecemeal microautophagy of the nucleus

determination method

1 reference

16 July 2018

Piecemeal microautophagy of the nucleus requires the core macroautophagy genes.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38862&geneProductId=UniProtKB:P38862

determination method

autophagosome assembly

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

cellular response to nitrogen starvation

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

C-terminal protein lipidation

determination method

7 references

9 May 2019

The carboxyl terminal 17 amino acids within Apg7 are essential for Apg8 lipidation, but not for Apg12 conjugation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

9 May 2019

In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

9 May 2019

The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

9 May 2019

A ubiquitin-like system mediates protein lipidation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

9 May 2019

Mutation at the cargo-receptor binding site of Atg8 also affects its general autophagy regulation function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

9 May 2019

In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38862

determination method

Ubiquitin-like modifier-activating enzyme Atg7, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P38862

THIF-type NAD/FAD binding fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P38862

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Saccharomyces Genome Database ID

1 reference

20 March 2022

Sitelinks

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