(Q27549765)

English

Atg12p YBR217W

fungal protein found in Saccharomyces cerevisiae S288c

YBR217W
Atg12p
ATG12

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

Ubiquitin-like protein Atg12

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P38316

Ubiquitin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P38316

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

enzyme activator activity

determination method

1 reference

14 February 2019

Atg12-Atg5 conjugate enhances E2 activity of Atg3 by rearranging its catalytic site

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

Atg8 ligase activity

determination method

1 reference

27 February 2018

The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38316&geneProductId=UniProtKB:P38316

determination method

determination method

3 references

14 February 2019

Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

14 February 2019

A protein conjugation system essential for autophagy

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

14 February 2019

Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

protein binding

determination method

7 references

14 February 2019

Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

14 February 2019

A comprehensive two-hybrid analysis to explore the yeast protein interactome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

14 February 2019

Structure of the Atg12–Atg5 conjugate reveals a platform for stimulating Atg8–PE conjugation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

14 February 2019

Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

14 February 2019

Assigning function to yeast proteins by integration of technologies.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

14 February 2019

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

14 February 2019

A protein conjugation system essential for autophagy

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

phagophore assembly site

determination method

1 reference

14 February 2019

Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

Atg12-Atg5-Atg16 complex

determination method

1 reference

27 February 2018

Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38316&geneProductId=UniProtKB:P38316

determination method

Atg12-Atg5-Atg16 complex

determination method

determination method

1 reference

14 February 2019

One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

biological process

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

autophagy of mitochondrion

determination method

1 reference

27 February 2018

A genomic screen for yeast mutants defective in selective mitochondria autophagy

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38316&geneProductId=UniProtKB:P38316

determination method

C-terminal protein lipidation

determination method

1 reference

27 February 2018

The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38316&geneProductId=UniProtKB:P38316

determination method

piecemeal microautophagy of the nucleus

determination method

1 reference

14 February 2019

Piecemeal microautophagy of the nucleus requires the core macroautophagy genes.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

protein transport

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

cytoplasm to vacuole transport by the Cvt pathway

determination method

1 reference

14 February 2019

A protein conjugation system essential for autophagy

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

late nucleophagy

determination method

1 reference

14 February 2019

A late form of nucleophagy in Saccharomyces cerevisiae

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

positive regulation of catalytic activity

determination method

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

protein lipidation involved in autophagosome assembly

determination method

1 reference

14 February 2019

Molecular mechanism of autophagic membrane-scaffold assembly and disassembly.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

autophagosome assembly

determination method

3 references

14 February 2019

Structure-function relationship of Atg12, a ubiquitin-like modifier essential for autophagy

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Saccharomyces Genome Database ID

1 reference

20 March 2022

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