(Q27552599)

English

Serine C-palmitoyltransferase LCB1 YMR296C

fungal protein found in Saccharomyces cerevisiae S288c

LCB1
YMR296C
serine C-palmitoyltransferase LCB1

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Statements

1 reference

25 May 2022

Pyridoxal phosphate-dependent transferase, major domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P25045

Pyridoxal phosphate-dependent transferase domain 1

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P25045

Pyridoxal phosphate-dependent transferase

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P25045

membrane proteins

1 reference

based on heuristic

inferred from GOA cell component → membrane

Aminotransferase, class I/classII, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

serine C-palmitoyltransferase activity

3 references

9 May 2019

Characterization of enzymatic synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae: mutant strains exhibiting long-chain-base auxotrophy are deficient in serine palmitoyltransferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

9 May 2019

The LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

determination method

IEA

acyltransferase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

determination method

IEA

pyridoxal phosphate binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

4 references

9 May 2019

Proteome survey reveals modularity of the yeast cell machinery

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

9 May 2019

Orm family proteins mediate sphingolipid homeostasis

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

9 May 2019

Tsc3p is an 80-amino acid protein associated with serine palmitoyltransferase and required for optimal enzyme activity

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

9 May 2019

Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

determination method

IPI

cell component

integral component of membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

determination method

IEA

serine C-palmitoyltransferase complex

1 reference

9 May 2019

Characterization of enzymatic synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae: mutant strains exhibiting long-chain-base auxotrophy are deficient in serine palmitoyltransferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

determination method

IMP

endoplasmic reticulum membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

determination method

IEA

endoplasmic reticulum

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25045&geneProductId=UniProtKB:P25045

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

determination method

IEA

sphingolipid metabolic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

determination method

IEA

sphingolipid biosynthetic process

1 reference

9 May 2019

Characterization of enzymatic synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae: mutant strains exhibiting long-chain-base auxotrophy are deficient in serine palmitoyltransferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25045

determination method

IMP

has part(s)

Aminotransferase, class I/classII

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P25045

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

Saccharomyces Genome Database ID

1 reference

20 March 2022

(Q27552599)

Serine C-palmitoyltransferase LCB1 YMR296C

Statements

Identifiers

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