(Q27553163)

English

Atg5p YPL149W

fungal protein found in Saccharomyces cerevisiae S288c

Atg5p
YPL149W
ATG5

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

enzyme activator activity

determination method

1 reference

14 February 2019

Atg12-Atg5 conjugate enhances E2 activity of Atg3 by rearranging its catalytic site

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

hydrolase activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

Atg8 ligase activity

determination method

1 reference

27 February 2018

The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12380&geneProductId=UniProtKB:Q12380

determination method

protein binding

determination method

7 references

14 February 2019

Structure of the Atg12–Atg5 conjugate reveals a platform for stimulating Atg8–PE conjugation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

14 February 2019

Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

14 February 2019

High-quality binary protein interaction map of the yeast interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

14 February 2019

Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

14 February 2019

Assigning function to yeast proteins by integration of technologies.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

14 February 2019

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

14 February 2019

A protein conjugation system essential for autophagy

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

determination method

1 reference

14 February 2019

Atg21 is a phosphoinositide binding protein required for efficient lipidation and localization of Atg8 during uptake of aminopeptidase I by selective autophagy

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

Atg12-Atg5-Atg16 complex

determination method

1 reference

27 February 2018

Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12380&geneProductId=UniProtKB:Q12380

determination method

determination method

1 reference

10 September 2018

Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12380&geneProductId=UniProtKB:Q12380

determination method

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

phagophore assembly site

determination method

determination method

1 reference

14 February 2019

Fine mapping of autophagy-related proteins during autophagosome formation in Saccharomyces cerevisiae

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

vacuole-isolation membrane contact site

determination method

1 reference

14 February 2019

Fine mapping of autophagy-related proteins during autophagosome formation in Saccharomyces cerevisiae

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

Atg12-Atg5-Atg16 complex

determination method

determination method

1 reference

14 February 2019

One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

determination method

biological process

determination method

2 references

autophagy of mitochondrion

determination method

1 reference

27 February 2018

A genomic screen for yeast mutants defective in selective mitochondria autophagy

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12380&geneProductId=UniProtKB:Q12380

determination method

determination method

1 reference

14 February 2019

Structural and functional analyses of APG5, a gene involved in autophagy in yeast

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

C-terminal protein lipidation

determination method

1 reference

27 February 2018

The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12380&geneProductId=UniProtKB:Q12380

determination method

cellular response to nitrogen starvation

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

piecemeal microautophagy of the nucleus

determination method

1 reference

14 February 2019

Piecemeal microautophagy of the nucleus requires the core macroautophagy genes.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

protein transport

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

cytoplasm to vacuole transport by the Cvt pathway

determination method

1 reference

14 February 2019

Apg5p functions in the sequestration step in the cytoplasm-to-vacuole targeting and macroautophagy pathways

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

late nucleophagy

determination method

1 reference

14 February 2019

A late form of nucleophagy in Saccharomyces cerevisiae

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

autophagosome assembly

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

positive regulation of catalytic activity

determination method

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12380

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Saccharomyces Genome Database ID

1 reference

20 March 2022

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