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PIK3CA Exon 10 Mutation
genetic variant
EXON 10 MUTATION
EXON 9 MUTATION
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Statements
instance of
exon variant
1 reference
stated in
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/variants/106
chromosome
human chromosome 3
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/variants/106
genomic start
178935998
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/variants/106
genomic end
178936122
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/variants/106
biological variant of
PIK3CA
1 reference
stated in
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/variants/106
negative therapeutic predictor for
cetuximab / chemotherapy combination therapy
determination method
CIViC evidence level B
rating
CIViC 3-star trust rating
medical condition treated
colorectal cancer
statement disputed by
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis
1 reference
curator
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/123
stated in
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis
negative prognostic predictor for
colorectal cancer
determination method
CIViC evidence level B
rating
CIViC 2-star trust rating
statement disputed by
Prognostic Role of PIK3CA Mutation in Colorectal Cancer: Cohort Study and Literature Review
1 reference
curator
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/384
stated in
Prognostic Role of PIK3CA Mutation in Colorectal Cancer: Cohort Study and Literature Review
breast cancer
determination method
CIViC evidence level B
rating
CIViC 4-star trust rating
1 reference
curator
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/6199
stated in
Different prognostic roles of mutations in the helical and kinase domains of the PIK3CA gene in breast carcinomas
Identifiers
CIViC variant ID
106
1 reference
stated in
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/variants/106
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