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KRAS RS61764370
genetic variant
RS61764370
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Statements
instance of
3 Prime UTR Variant
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/254
chromosome
human chromosome 12
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/254
genomic start
25360224
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/254
genomic end
25360224
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/254
biological variant of
KRAS
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/254
negative therapeutic predictor for
paclitaxel
determination method
CIViC evidence level B
rating
CIViC 3-star trust rating
medical condition treated
surface epithelial-stromal tumor
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/664
stated in
A KRAS variant is a biomarker of poor outcome, platinum chemotherapy resistance and a potential target for therapy in ovarian cancer
cisplatin
determination method
CIViC evidence level B
rating
CIViC 3-star trust rating
medical condition treated
head and neck squamous cell carcinoma
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/872
stated in
A 3'-UTR KRAS-variant is associated with cisplatin resistance in patients with recurrent and/or metastatic head and neck squamous cell carcinoma
carboplatin
determination method
CIViC evidence level B
rating
CIViC 3-star trust rating
medical condition treated
surface epithelial-stromal tumor
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/664
stated in
A KRAS variant is a biomarker of poor outcome, platinum chemotherapy resistance and a potential target for therapy in ovarian cancer
Identifiers
CIViC variant ID
254
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/254
dbSNP Reference SNP number
rs61764370
1 reference
stated in
CIViC database
HGVS nomenclature
NC_000012.11:g.25360224A>C
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/254
NM_004985.4:c.*2505T>G
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/254
ENST00000311936.3:c.*2505T>G
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/254
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