(Q28444963)

English

DNMT3A Mutation

genetic variant

MUTATION

In more languages

Statements

transcript variant

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/variants/189

human chromosome 2

genomic assembly

Genome assembly GRCh37

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/variants/189

25455845

genomic assembly

Genome assembly GRCh37

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/variants/189

25565459

genomic assembly

Genome assembly GRCh37

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/variants/189

biological variant of

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/variants/189

positive therapeutic predictor for

medical condition treated

acute myeloid leukemia

determination method

CIViC evidence level B

CIViC 3-star trust rating

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/evidence/1587

DNMT3A mutations and response to the hypomethylating agent decitabine in acute myeloid leukemia

negative therapeutic predictor for

determination method

CIViC evidence level B

CIViC 2-star trust rating

medical condition treated

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/evidence/2926

Hyperprogressors after Immunotherapy: Analysis of Genomic Alterations Associated with Accelerated Growth Rate

determination method

CIViC evidence level B

CIViC 2-star trust rating

medical condition treated

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/evidence/2926

Hyperprogressors after Immunotherapy: Analysis of Genomic Alterations Associated with Accelerated Growth Rate

determination method

CIViC evidence level B

CIViC 2-star trust rating

medical condition treated

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/evidence/2926

Hyperprogressors after Immunotherapy: Analysis of Genomic Alterations Associated with Accelerated Growth Rate

negative prognostic predictor for

acute myeloid leukemia

determination method

CIViC evidence level B

CIViC 3-star trust rating

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/evidence/188

Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia

myelodysplastic syndrome

determination method

CIViC evidence level B

CIViC 3-star trust rating

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/evidence/1238

Recurrent DNMT3A mutations in patients with myelodysplastic syndromes

acute myeloid leukemia

determination method

CIViC evidence level B

CIViC 4-star trust rating

2 references

23 May 2022

https://civic.genome.wustl.edu/links/evidence/1585

Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia.

23 May 2022

https://civic.genome.wustl.edu/links/evidence/1586

Genomic Classification and Prognosis in Acute Myeloid Leukemia

acute T cell leukemia

determination method

CIViC evidence level B

CIViC 4-star trust rating

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/evidence/469

The molecular profile of adult T-cell acute lymphoblastic leukemia: mutations in RUNX1 and DNMT3A are associated with poor prognosis in T-ALL.

Identifiers

CIViC variant ID

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/variants/189

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