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RET Overexpression
genetic variant
Overexpression
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Statements
instance of
sequence variant
1 reference
stated in
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/variants/597
chromosome
human chromosome 10
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/variants/597
genomic start
43572475
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/variants/597
genomic end
43625799
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/variants/597
biological variant of
RET
1 reference
stated in
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/variants/597
positive therapeutic predictor for
sunitinib
medical condition treated
papillary adenocarcinoma
determination method
CIViC evidence level C
rating
CIViC 3-star trust rating
1 reference
curator
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/1518
stated in
Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors
vandetanib
determination method
CIViC evidence level D
rating
CIViC 2-star trust rating
medical condition treated
breast cancer
1 reference
curator
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/740
stated in
Vandetanib as a potential new treatment for estrogen receptor-negative breast cancers.
negative prognostic predictor for
adenocarcinoma of the lung
determination method
CIViC evidence level B
rating
CIViC 3-star trust rating
1 reference
curator
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/7056
stated in
ASCL1 and RET expression defines a clinically relevant subgroup of lung adenocarcinoma characterized by neuroendocrine differentiation
Identifiers
CIViC variant ID
597
1 reference
stated in
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/variants/597
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