(Q28555976)

membrane protein

1 reference

inferred from GOA cell component → membrane

Notch ligand, N-terminal domain, protein family

1 reference

Delta/Serrate/lag-2 (DSL) protein family

1 reference

EGF-like calcium-binding domain, protein family

1 reference

EGF-like domain, protein family

1 reference

EGF-like, conserved site, protein family

1 reference

EGF-like calcium-binding, conserved site, protein family

1 reference

Patterns of Jagged1, Jagged2, Delta-like 1 and Delta-like 3 expression during late embryonic and postnatal brain development suggest multiple functional roles in progenitors and differentiated cells

1 reference

25 May 2022

1 reference

25 May 2022

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

14 February 2019

Human ligands of the Notch receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

14 February 2019

Deciphering the Fringe-Mediated Notch Code: Identification of Activating and Inhibiting Sites Allowing Discrimination between Ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

14 February 2019

Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

1 reference

9 May 2019

Notch ligand endocytosis generates mechanical pulling force dependent on dynamin, epsins, and actin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

5 references

9 May 2019

Patterns of Jagged1, Jagged2, Delta-like 1 and Delta-like 3 expression during late embryonic and postnatal brain development suggest multiple functional roles in progenitors and differentiated cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

9 May 2019

Human ligands of the Notch receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

9 May 2019

Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

9 May 2019

Deciphering the Fringe-Mediated Notch Code: Identification of Activating and Inhibiting Sites Allowing Discrimination between Ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

2 references

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

cell fate determination

1 reference

9 May 2019

Patterns of Jagged1, Jagged2, Delta-like 1 and Delta-like 3 expression during late embryonic and postnatal brain development suggest multiple functional roles in progenitors and differentiated cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

marginal zone B cell differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

type B pancreatic cell development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

Reactivation of Delta-Notch signaling after injury: complementary expression patterns of ligand and receptor in dental pulp

IEA

Notch signaling pathway

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

nervous system development

IEA

1 reference

9 May 2019

Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

regulation of blood pressure

NAS

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

positive regulation of cell population proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

negative regulation of cell population proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

auditory receptor cell fate commitment

1 reference

9 May 2019

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

proximal/distal pattern formation

NAS

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

astrocyte development

1 reference

9 May 2019

regulation of somitogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

spinal cord development

1 reference

9 May 2019

cerebellar molecular layer formation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

cerebellar Purkinje cell layer structural organization

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

negative regulation of epithelial cell differentiation

IEA

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

negative regulation of glial cell apoptotic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

negative regulation of cell differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

negative regulation of epidermal cell differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

negative regulation of myoblast differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

negative regulation of neuron differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

positive regulation of endocytosis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

skeletal muscle tissue growth

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

regulation of skeletal muscle tissue growth

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

positive regulation of skeletal muscle tissue growth

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

neuron fate specification

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

regulation of neurogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

regulation of cell division

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

retina development in camera-type eye

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

retina morphogenesis in camera-type eye

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

Notch signaling pathway involved in arterial endothelial cell fate commitment

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

clathrin-dependent endocytosis

1 reference

9 May 2019

Notch ligand endocytosis generates mechanical pulling force dependent on dynamin, epsins, and actin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

endothelial tip cell fate specification

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

neuronal stem cell population maintenance

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

skin epidermis development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

regulation of vascular endothelial growth factor signaling pathway

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

positive regulation of sprouting angiogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

Reactivation of Delta-Notch signaling after injury: complementary expression patterns of ligand and receptor in dental pulp

Notch signaling pathway

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97677

EGF-like calcium-binding domain

IBA

has part(s)

1 reference

EGF-like domain

1 reference

Notch ligand, N-terminal domain

1 reference

Delta/Serrate/lag-2 (DSL) protein

1 reference

EGF-type aspartate/asparagine hydroxylation site

1 reference

EGF-like calcium-binding, conserved site

1 reference

EGF-like, conserved site

1 reference