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Nucleobindin 2
mammalian protein found in Rattus norvegicus
Nucb2
prepronefastin
nesfatin-1
nucleobindin-2
DNA-binding protein NEFA
prepronesfatin
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9JI85
part of
Nucleobindin-2
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9JI85
EF-hand domain pair
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9JI85
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
EF-hand domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
EF-Hand 1, calcium-binding site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
brown rat
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9JI85
encoded by
Nucb2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9JI85
molecular function
DNA binding
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9JI85
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IEA
tumor necrosis factor receptor binding
determination method
IPI
1 reference
retrieved
9 May 2019
stated in
14-Deoxyandrographolide desensitizes hepatocytes to tumour necrosis factor-alpha-induced apoptosis through calcium-dependent tumour necrosis factor receptor superfamily member 1A release via the NO/cGMP pathway
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IPI
calcium ion binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IEA
metal ion binding
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9JI85
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IEA
calcium ion binding
determination method
IBA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IBA
cell component
extracellular region
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9JI85
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IEA
extracellular space
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Identification of nesfatin-1 as a satiety molecule in the hypothalamus
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IDA
nucleus
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9JI85
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IEA
nuclear envelope
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9JI85
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IEA
cytoplasm
determination method
IDA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9JI85
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IEA
retrieved
9 May 2019
stated in
Nucleobindin-2/nesfatin in the endocrine pancreas: distribution and relationship to glycaemic state
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IDA
endoplasmic reticulum
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9JI85
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IEA
Golgi apparatus
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9JI85
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IEA
Golgi medial cisterna
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
The calcium-binding protein p54/NEFA is a novel luminal resident of medial Golgi cisternae that traffics independently of mannosidase II
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IDA
membrane
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9JI85
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IEA
endoplasmic reticulum-Golgi intermediate compartment
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IBA
biological process
response to glucose
determination method
IEP
1 reference
retrieved
9 May 2019
stated in
Nucleobindin-2/nesfatin in the endocrine pancreas: distribution and relationship to glycaemic state
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IEP
negative regulation of appetite
determination method
IEA
IMP
2 references
retrieved
9 May 2019
stated in
Identification of nesfatin-1 as a satiety molecule in the hypothalamus
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IMP
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IEA
response to starvation
determination method
IEP
1 reference
retrieved
9 May 2019
stated in
Cellular distribution, regulated expression, and functional role of the anorexigenic peptide, NUCB2/nesfatin-1, in the testis
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IEP
negative regulation of cAMP-mediated signaling
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Secreted nucleobindin-2 inhibits 3T3-L1 adipocyte differentiation
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IDA
response to human chorionic gonadotropin
determination method
IEP
1 reference
retrieved
9 May 2019
stated in
Cellular distribution, regulated expression, and functional role of the anorexigenic peptide, NUCB2/nesfatin-1, in the testis
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IEP
negative regulation of fat cell differentiation
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Secreted nucleobindin-2 inhibits 3T3-L1 adipocyte differentiation
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IDA
positive regulation of fatty acid oxidation
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Nutrient responsive nesfatin-1 regulates energy balance and induces glucose-stimulated insulin secretion in rats
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IDA
negative regulation of insulin receptor signaling pathway
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Secreted nucleobindin-2 inhibits 3T3-L1 adipocyte differentiation
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IDA
negative regulation of glucagon secretion
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Nutrient responsive nesfatin-1 regulates energy balance and induces glucose-stimulated insulin secretion in rats
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IDA
insulin metabolic process
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Nutrient responsive nesfatin-1 regulates energy balance and induces glucose-stimulated insulin secretion in rats
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IDA
response to melanocyte-stimulating hormone
determination method
IEP
1 reference
retrieved
9 May 2019
stated in
Identification of nesfatin-1 as a satiety molecule in the hypothalamus
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IEP
positive regulation of testosterone secretion
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Cellular distribution, regulated expression, and functional role of the anorexigenic peptide, NUCB2/nesfatin-1, in the testis
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JI85
determination method
IDA
has part(s)
EF-hand 1, calcium-binding site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9JI85
EF-hand domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9JI85
Identifiers
RefSeq protein ID
NP_067695
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
59295
XP_006230157
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
59295
UniProt protein ID
Q9JI85
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9JI85
Ensembl protein ID
ENSRNOP00000027753
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000027753
ENSRNOP00000088880
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000088880
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