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(Q28557337)
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Epsin 1
mammalian protein found in Rattus norvegicus
EPS-15-interacting protein 1
Epn1
epsin-1
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
O88339
part of
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
found in taxon
brown rat
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
O88339
encoded by
Epn1
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
O88339
molecular function
protein binding
determination method
IPI
2 references
retrieved
14 February 2019
stated in
Notch ligand endocytosis generates mechanical pulling force dependent on dynamin, epsins, and actin
GOA
curator
UniProt
UniProt protein ID
O88339
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IPI
retrieved
14 February 2019
stated in
Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IPI
transcription factor binding
determination method
IPI
1 reference
retrieved
14 February 2019
stated in
Epsin 1 undergoes nucleocytosolic shuttling and its eps15 interactor NH(2)-terminal homology (ENTH) domain, structurally similar to Armadillo and HEAT repeats, interacts with the transcription factor promyelocytic leukemia Zn(2)+ finger protein (PLZ
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IPI
lipid binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88339
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IEA
clathrin adaptor activity
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Unusual structural organization of the endocytic proteins AP180 and epsin 1
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IMP
transmembrane transporter binding
determination method
IPI
1 reference
retrieved
14 February 2019
stated in
Purification of an EH domain-binding protein from rat brain that modulates the gating of the rat ether-à-go-go channel
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IPI
cell component
nucleus
determination method
IDA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88339
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IEA
retrieved
14 February 2019
stated in
Deletion of a conserved noncoding sequence in Plzf intron leads to Plzf down-regulation in limb bud and polydactyly in the rat
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IDA
cytoplasm
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88339
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IEA
cytosol
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Unusual structural organization of the endocytic proteins AP180 and epsin 1
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IDA
plasma membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88339
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IEA
clathrin-coated pit
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88339
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88339
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IEA
extrinsic component of cytoplasmic side of plasma membrane
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Partially overlapping distribution of epsin1 and HIP1 at the synapse: analysis by immunoelectron microscopy
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IDA
terminal bouton
determination method
HDA
1 reference
retrieved
14 February 2019
stated in
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
HDA
Schaffer collateral - CA1 synapse
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Partially overlapping distribution of epsin1 and HIP1 at the synapse: analysis by immunoelectron microscopy
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IDA
presynapse
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Partially overlapping distribution of epsin1 and HIP1 at the synapse: analysis by immunoelectron microscopy
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IDA
postsynapse
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Partially overlapping distribution of epsin1 and HIP1 at the synapse: analysis by immunoelectron microscopy
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IDA
extrinsic component of presynaptic membrane
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Partially overlapping distribution of epsin1 and HIP1 at the synapse: analysis by immunoelectron microscopy
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IDA
extrinsic component of postsynaptic membrane
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Partially overlapping distribution of epsin1 and HIP1 at the synapse: analysis by immunoelectron microscopy
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IDA
biological process
endocytosis
determination method
IDA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88339
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IEA
retrieved
14 February 2019
stated in
Curvature of clathrin-coated pits driven by epsin
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IDA
receptor-mediated endocytosis
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IEA
positive regulation of clathrin coat assembly
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Unusual structural organization of the endocytic proteins AP180 and epsin 1
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88339
determination method
IMP
Identifiers
RefSeq protein ID
NP_476477
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
117277
XP_038935182
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
117277
XP_038935223
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
117277
XP_038935258
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
117277
XP_038935289
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
117277
XP_038935327
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
117277
XP_038935365
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
117277
XP_038935421
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
117277
XP_038935458
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
117277
XP_038935502
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
117277
XP_038935545
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
117277
XP_038935584
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
117277
UniProt protein ID
O88339
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
O88339
Ensembl protein ID
ENSRNOP00000021286
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000021286
ENSRNOP00000092218
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000092218
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