(Q28558486)

http://www.ebi.ac.uk/interpro/protein/O55170

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

High mobility group box domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Sox developmental protein N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

DNA-binding transcription activator activity, RNA polymerase II-specific

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

1 reference

14 February 2019

The high-mobility group transcription factor Sox10 interacts with the N-myc-interacting protein Nmi

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

transcription factor binding

IPI

3 references

14 February 2019

The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

14 February 2019

The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

identical protein binding

IDA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

promoter-specific chromatin binding

1 reference

14 February 2019

SOX10 regulates expression of the SH3-domain kinase binding protein 1 (Sh3kbp1) locus in Schwann cells via an alternative promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

1 reference

14 February 2019

SOX10 regulates an alternative promoter at the Charcot-Marie-Tooth disease locus MTMR2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

14 February 2019

Sox10 is an active nucleocytoplasmic shuttle protein, and shuttling is crucial for Sox10-mediated transactivation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

14 February 2019

Sox10 is an active nucleocytoplasmic shuttle protein, and shuttling is crucial for Sox10-mediated transactivation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

mitochondrial outer membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

extrinsic component of mitochondrial outer membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

in utero embryonic development

biological process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

morphogenesis of an epithelium

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

positive regulation of neuroblast proliferation

IBA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

regulation of transcription, DNA-templated

1 reference

14 February 2019

Sox10, a novel transcriptional modulator in glial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

transcription elongation from RNA polymerase II promoter

IDA

1 reference

14 February 2019

Transcription factors Sox10 and Sox2 functionally interact with positive transcription elongation factor b in Schwann cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

central nervous system development

IDA

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

negative regulation of Schwann cell proliferation

IBA

1 reference

14 February 2019

SOX10 transactivates S100B to suppress Schwann cell proliferation and to promote myelination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

positive regulation of gene expression

IMP

1 reference

14 February 2019

Cell type-specific activation of neuronal nicotinic acetylcholine receptor subunit genes by Sox10.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

positive regulation of gliogenesis

IMP

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

melanocyte differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

positive regulation of myelination

1 reference

14 February 2019

SOX10 transactivates S100B to suppress Schwann cell proliferation and to promote myelination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

lacrimal gland development

IMP

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

negative regulation of apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

negative regulation of transcription, DNA-templated

1 reference

14 February 2019

The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

1 reference

14 February 2019

Sox10, a novel transcriptional modulator in glial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

digestive tract morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

oligodendrocyte differentiation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

stem cell differentiation

IBA

1 reference

14 February 2019

SOX10 Maintains Multipotency and Inhibits Neuronal Differentiation of Neural Crest Stem Cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

morphogenesis of a branching epithelium

IEP

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

cellular response to progesterone stimulus

1 reference

14 February 2019

Progesterone derivatives increase expression of Krox-20 and Sox-10 in rat Schwann cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

negative regulation of canonical Wnt signaling pathway

IEP

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55170

High mobility group box domain

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O55170

Sox developmental protein N-terminal

1 reference

stated in

InterPro Release 71.0