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(Q28561579)
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Hepatocyte growth factor-regulated tyrosine kinase substrate
mammalian protein found in Rattus norvegicus
HGF-regulated tyrosine kinase substrate
Hgs
hepatocyte growth factor-regulated tyrosine kinase substrate
SNAP-25-interacting protein Hrs-2
In more languages
default for all languages
No label defined
No description defined
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9JJ50
part of
Zinc finger, FYVE/PHD-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9JJ50
ENTH/VHS
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9JJ50
Zinc finger, RING/FYVE/PHD-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9JJ50
Ubiquitin binding protein, Hrs/VPS27
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9JJ50
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
FYVE zinc finger, protein family
1 reference
based on heuristic
inferred from protein domain or family
Zinc finger, FYVE-related, protein family
1 reference
based on heuristic
inferred from protein domain or family
VHS domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Ubiquitin interacting motif, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
brown rat
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9JJ50
encoded by
Hgs
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9JJ50
molecular function
protein binding
determination method or standard
IPI
3 references
retrieved
14 February 2019
stated in
Hrs interacts with sorting nexin 1 and regulates degradation of epidermal growth factor receptor
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JJ50
determination method or standard
IPI
retrieved
14 February 2019
stated in
Hrs interacts with SNAP-25 and regulates Ca(2+)-dependent exocytosis
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JJ50
determination method or standard
IPI
retrieved
14 February 2019
stated in
Huntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated tyrosine kinase substrate and functions in endosomal trafficking
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JJ50
determination method or standard
IPI
protein domain specific binding
determination method or standard
NAS
1 reference
retrieved
14 February 2019
stated in
Hrs interacts with SNAP-25 and regulates Ca(2+)-dependent exocytosis
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JJ50
determination method or standard
NAS
metal ion binding
determination method or standard
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9JJ50
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JJ50
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JJ50
determination method or standard
IEA
cell component
cytoplasm
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9JJ50
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JJ50
determination method or standard
IEA
endosome
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9JJ50
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JJ50
determination method or standard
IEA
cytosol
determination method or standard
IDA
1 reference
retrieved
14 February 2019
stated in
Hrs interacts with SNAP-25 and regulates Ca(2+)-dependent exocytosis
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JJ50
determination method or standard
IDA
membrane
determination method or standard
IDA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9JJ50
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JJ50
determination method or standard
IEA
retrieved
14 February 2019
stated in
Hrs interacts with SNAP-25 and regulates Ca(2+)-dependent exocytosis
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JJ50
determination method or standard
IDA
secretory granule
determination method or standard
IDA
1 reference
retrieved
14 February 2019
stated in
Hrs interacts with SNAP-25 and regulates Ca(2+)-dependent exocytosis
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JJ50
determination method or standard
IDA
early endosome membrane
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9JJ50
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JJ50
determination method or standard
IEA
multivesicular body membrane
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9JJ50
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JJ50
determination method or standard
IEA
biological process
intracellular protein transport
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JJ50
determination method or standard
IEA
endosome to lysosome transport
determination method or standard
IMP
1 reference
retrieved
14 February 2019
stated in
Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JJ50
determination method or standard
IMP
protein transport
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9JJ50
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JJ50
determination method or standard
IEA
has part(s)
Zinc finger, FYVE-related
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9JJ50
Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9JJ50
FYVE zinc finger
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9JJ50
Ubiquitin interacting motif
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9JJ50
VHS domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9JJ50
Identifiers
RefSeq protein ID
NP_062260
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
56084
XP_006247970
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
56084
XP_006247971
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
56084
XP_038942636
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
56084
XP_038942637
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
56084
XP_038942638
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
56084
XP_038942640
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
56084
NP_001386548
1 reference
stated in
NCBI Gene
retrieved
14 January 2022
Entrez Gene ID
56084
NP_001386549
1 reference
stated in
NCBI Gene
retrieved
14 January 2022
Entrez Gene ID
56084
UniProt protein ID
Q9JJ50
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9JJ50
Ensembl protein ID
ENSRNOP00000051849
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000051849
ENSRNOP00000087685
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000087685
Sitelinks
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