(Q28561637)

English

Progesterone receptor membrane component 1

mammalian protein found in Rattus norvegicus

acidic 25 kDa protein
membrane-bound progesterone receptor
Pgrmc1
ventral midline antigen
membrane-associated progesterone receptor component 1

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Statements

1 reference

25 May 2022

cytochrome b5-like heme/steroid binding domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P70580

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

cytochrome b5-like heme/steroid binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

1 reference

14 February 2019

Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

determination method

TAS

cell component

endoplasmic reticulum

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

1 reference

14 February 2019

Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

determination method

IEA

integral component of membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

determination method

IEA

smooth endoplasmic reticulum membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

1 reference

14 February 2019

Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

1 reference

14 February 2019

Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

determination method

IDA

intracellular membrane-bounded organelle

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

1 reference

14 February 2019

Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

1 reference

14 February 2019

Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

1 reference

14 February 2019

Cloning and expression of VEMA: a novel ventral midline antigen in the rat CNS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

1 reference

14 February 2019

Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers I: Abeta 42 oligomer binding to specific neuronal receptors is displaced by drug candidates that improve cognitive deficits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

1 reference

14 February 2019

Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers I: Abeta 42 oligomer binding to specific neuronal receptors is displaced by drug candidates that improve cognitive deficits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

determination method

IGI

modification of synaptic structure

1 reference

14 February 2019

Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers I: Abeta 42 oligomer binding to specific neuronal receptors is displaced by drug candidates that improve cognitive deficits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

determination method

IGI

positive regulation of protein localization to plasma membrane

1 reference

14 February 2019

Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

determination method

IMP

negative regulation of synapse organization

1 reference

14 February 2019

Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers I: Abeta 42 oligomer binding to specific neuronal receptors is displaced by drug candidates that improve cognitive deficits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70580

determination method

IGI

has part(s)

cytochrome b5-like heme/steroid binding domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P70580

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

(Q28561637)

Progesterone receptor membrane component 1

Statements

Identifiers

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